Synthesis of New Heterocycles Incorporating 3-(N-phthalimidomethyl)-1,2,4-triazole as Antimicrobial Agents | ||||
Egyptian Journal of Chemistry | ||||
Article 5, Volume 59, Issue 5, October 2016, Page 731-744 PDF (565.79 K) | ||||
DOI: 10.21608/ejchem.2016.1447 | ||||
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Abstract | ||||
NOVEL series of 1,2,4-triazole Schiff’s bases;1,2,4-……..triazolothiadiazinesand triazolothiadiazoles was prepared from reaction of 4-amino-3-(N-phthalimidomethyl)-1,2,4-triazole-5-thione and different aldehydes, hydrazonyl chlorides, 𝛼-haloketones, and substituted benzoic acids. The products have been evaluated for their antimicrobial activity and the Schiff’s bases were found to exhibit an antimicrobial activity. | ||||
Keywords | ||||
Triazole-5-thione; Phthalimide; Schiff’s base; Triazolothiadiazine; Triazolothiadiazole and Antimicrobial activity | ||||
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