PHYTOCHEMICAL AND BIOLOGICAL STUDY OF ERANTHEMUM NERVOSUM (VAHL) R. BR., CULTIVATED IN EGYPT | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 3, Volume 33, Issue 1, June 2010, Page 19-31 PDF (471.52 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.2010.147012 | ||||
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Authors | ||||
Mahmoud H. Assaf1; Yaser G. Gouda1; Ehab S. El-Khayat2; Reda A. Abd El-Hamid2 | ||||
1Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||||
2Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt | ||||
Abstract | ||||
Fractionation and purification of the methanolic extract of the aerial parts of Eranthemum nervosum (Vahl) R. Br. (Acanthaceae) cultivated in Egypt yielded eleven compounds named: β-amyrin (1), α-amyrin (2), Lupeol (3), β-sitosterol (4), Apigenin (5), Kaempferol (6), β-sitosterol 3-O-β-D-glucopyranoside (7), Benzoic acid (8), Kaempferol-3-O-β-D-glucopyranoside (9), Syringin (10) and Apigenin 7-O-neohesperidoside (11). Identification of these compounds has been established by physical, chemical and spectral data as well as comparison with authentic samples. The LD50; anti-inflammatory; antipyretic; hepatoprotective and the effect on CNS were studied. | ||||
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