Pathogenic Effects of Ethion Residues and the Expected Protective Role of the Ethanolic Extract of Rosemary (Rosmarinus Officinalis L.) Leaves in Male Rats | ||||
Egyptian Journal of Chemistry | ||||
Article 16, Volume 64, Issue 4, April 2021, Page 1817-1829 PDF (2.04 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejchem.2021.59950.3282 | ||||
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Authors | ||||
Hassan Abdel-Gawad 1; soliman soliman2; hamdy taha3; Mohamed Aly 4; Monira A. Abd El Kader5; Bahira Hegazi2 | ||||
1Applied Organic Chem., Pesticides, NRC | ||||
2Applied Organic Chemistry Department, Chemical Industries Research Division, National Research Centre, 33 EL Buhouth St., Dokki, Giza, 12622, Egypt | ||||
3Applied organic chemistry N R C | ||||
4Department of Animal Reproduction and Artificial Insemination, Veterinary Research Division, National Research Centre, National Research Centre, Egypt | ||||
53Biochemistry Department, Genetic Engineering and Biotechnology Division, National Research Centre, National Research Centre, Egypt | ||||
Abstract | ||||
Organophosphate insecticides (OPI) poisoning remains a major cause of morbidity and mortality in the third world countries. The continuous use of these pesticides tends to leave residues of these pesticides in agricultural crops, which in turn may harm people. The present study aimed to investigate the pathogenic effects of the "ethion" residues and the expected protective role of the ethanolic extract of rosemary (Rosmarinus officinalis L.) (EER), in adult male rats. Feeding animals with Maize containing ethion residues (4 mg/Kg) caused elevation in serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) activities (P | ||||
Keywords | ||||
Ethion; maize; rosemary; hepatotoxicity; nephrotoxicity; lipid profile; oxidative stress | ||||
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