Synthesis, Identification and Study of the Anti-microbial Activity of Novel Chalcone and Epoxy Chalcone Compounds | ||||
| Egyptian Journal of Chemistry | ||||
| Article 6, Volume 64, Issue 5, May 2021, Page 2297-2304 PDF (550.75 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2021.57012.3233 | ||||
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| Authors | ||||
Kawkab Ali   1; Nezar latif Shihab2; Bahjat ali saeed2
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| 1Department of Chemistry, College of Education for Pure Sciences, University of Basrah , Basrah, Iraq | ||||
| 2Department of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq. | ||||
| Abstract | ||||
| Abstract In this study, new chalcone and epoxy chalcone synthesized by condensation of 4-acetylbiphenyl with the appropriate aldehydes. The epoxy chalcone prepared via the reaction chalcone with alkaline hydrogen peroxide in methanol. We characterized their mass spectra and 1H, 13C-NMR, and 2D-HSQC spectra to confirm their structure and absolute configuration. The target compounds were then screened for their potential antibacterial and antifungal activities. Most of the tested chalcone compounds had better activity against the fungal strains Fusarium and Aspergillus niger. | ||||
| Keywords | ||||
| Chalcone; Epoxy Chalcone; Green Chemistry; Anti-microbial activity | ||||
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