Comparative phytochemical and biological studies of lipoidal matter of Ipomoea tricolor (Cav.) and Ipomoea fistulosa (Mart. Ex Choisy ) growing in Egypt
El Hawary, S., Ibrahim, N., Aly, H., Matlob, A., Dosoky, M., Abd Elhady Deabes, D., Selim, N. (2021). Comparative phytochemical and biological studies of lipoidal matter of Ipomoea tricolor (Cav.) and Ipomoea fistulosa (Mart. Ex Choisy ) growing in Egypt. EKB Journal Management System, 64(4), 1845-1857. doi: 10.21608/ejchem.2021.61245.3316
Seham El Hawary; Nabaweya Ali Ibrahim; Hanan F Aly; Azza Matlob; Magdy Mohammed Dosoky; Doaa Abd Elhady Deabes; Nabil Mohamed Selim. "Comparative phytochemical and biological studies of lipoidal matter of Ipomoea tricolor (Cav.) and Ipomoea fistulosa (Mart. Ex Choisy ) growing in Egypt". EKB Journal Management System, 64, 4, 2021, 1845-1857. doi: 10.21608/ejchem.2021.61245.3316
El Hawary, S., Ibrahim, N., Aly, H., Matlob, A., Dosoky, M., Abd Elhady Deabes, D., Selim, N. (2021). 'Comparative phytochemical and biological studies of lipoidal matter of Ipomoea tricolor (Cav.) and Ipomoea fistulosa (Mart. Ex Choisy ) growing in Egypt', EKB Journal Management System, 64(4), pp. 1845-1857. doi: 10.21608/ejchem.2021.61245.3316
El Hawary, S., Ibrahim, N., Aly, H., Matlob, A., Dosoky, M., Abd Elhady Deabes, D., Selim, N. Comparative phytochemical and biological studies of lipoidal matter of Ipomoea tricolor (Cav.) and Ipomoea fistulosa (Mart. Ex Choisy ) growing in Egypt. EKB Journal Management System, 2021; 64(4): 1845-1857. doi: 10.21608/ejchem.2021.61245.3316

Comparative phytochemical and biological studies of lipoidal matter of Ipomoea tricolor (Cav.) and Ipomoea fistulosa (Mart. Ex Choisy ) growing in Egypt

Egyptian Journal of Chemistry
Article 18, Volume 64, Issue 4, April 2021, Page 1845-1857  XML PDF (819.71 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2021.61245.3316
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Authors
Seham El Hawaryorcid 1; Nabaweya Ali Ibrahim email orcid 2; Hanan F Alyorcid 3; Azza Matlob2; Magdy Mohammed Dosoky2; Doaa Abd Elhady Deabes2; Nabil Mohamed Selim1
1Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr el Aini Street, Cairo,11562, Egypt.
2Department of Pharmacognosy, National Research Centre; 33-Elbohouth St, (Former El-Tahrir St.), Dokki – Giza-Egypt. P.O.12622, ID: 60014618.
3Deprtment of Therapeutic Chemistry , National Research Centre (NRC),El Behouth St. , P.O.12622. Dokki, Giza, Egypt.
Abstract
GC/MS of unsaponifiable matter (USM) of Ipomoea tricolor (Cav.) and Ipomoea fistulosa (Mart. Ex Choisy) leaves were characterized by the identification of 22 and 33 compounds represented (95.88 and 91.82 %), respectively. It composed mainly of hydrocarbons and oxygenated compounds. The GC/MS of fatty acids methyl ester (FAME) led to the identification of 8 and 10 compounds for I. tricolor and I. fistulosa, respectively. Linolenic and palmatic acids were found as the predominant fatty acids. On the other hand, the petroleum erher extract of I. tricolor was fractionated on column chromatography to yield major compounds; 5-phenyldecane and 4-phenyldecane, as well as, triterpenes including β-amyrin, lupeol and simiarenol, in addition to α- amyrin, β-sitosterol, stigmasterol and α- amyrin acetate which isolated for the first time from this species. The petroleum ether extracts of I. tricolor and I. fistulosa showed a significant increase in DPPH inhibition activity at 0.01 and 0.05 ug/ml, respectively. Furthermore, I. tricolor extract exhibited a significant increase in cholinesterase inhibition activity at concentration 20 ug/ml and a significant anti-inflammatory activity with IC50 117.4µg/ml.
Keywords
Ipomoea tricolor; Ipomoea fistulosa; triterpenes; antioxidant; anticholinesterase; ant-inflammatory
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