Diabetes and COVID-19 comorbidity: Matters arising and public health implications
Abdulkarim, H., Abdulkarim, J., Muhammad, F., Yakubu, A., Adogo, L., Reuben, R. (2021). Diabetes and COVID-19 comorbidity: Matters arising and public health implications. EKB Journal Management System, 2(2), 197-203. doi: 10.21608/mid.2021.62493.1121
Hafsat Abdulkarim; Jamil Hassan Abdulkarim; Faisal Muhammad; Aliyu Yakubu; Lillian Yami Adogo; Rine Reuben. "Diabetes and COVID-19 comorbidity: Matters arising and public health implications". EKB Journal Management System, 2, 2, 2021, 197-203. doi: 10.21608/mid.2021.62493.1121
Abdulkarim, H., Abdulkarim, J., Muhammad, F., Yakubu, A., Adogo, L., Reuben, R. (2021). 'Diabetes and COVID-19 comorbidity: Matters arising and public health implications', EKB Journal Management System, 2(2), pp. 197-203. doi: 10.21608/mid.2021.62493.1121
Abdulkarim, H., Abdulkarim, J., Muhammad, F., Yakubu, A., Adogo, L., Reuben, R. Diabetes and COVID-19 comorbidity: Matters arising and public health implications. EKB Journal Management System, 2021; 2(2): 197-203. doi: 10.21608/mid.2021.62493.1121

Diabetes and COVID-19 comorbidity: Matters arising and public health implications

Microbes and Infectious Diseases
Article 4, Volume 2, Issue 2, May 2021, Page 197-203  XML PDF (218.3 K)
Document Type: Mini-review article
DOI: 10.21608/mid.2021.62493.1121
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Authors
Hafsat Abdulkarim1; Jamil Hassan Abdulkarim2; Faisal Muhammad3; Aliyu Yakubu4; Lillian Yami Adogo5; Rine Reuben email orcid 6
1Department of Biochemistry, Bauchi State University Gadau, Bauchi State, Nigeria
2Department of Environmental Health, New Gate College of Health Technology, Minna, Nigeria
3Department of Public Health, Faculty of Allied Health Sciences, Daffodil International University, Dhaka, Bangladesh
4Department of Science Laboratory Technology, Federal Polytechnic, Nasarawa, Nasarawa State, Nigeria
5Department of Biological Sciences, Bingham University, Karu, Nigeria
6Experimental Interactive Ecology German Centre of Integrative Biodiversity Research, Halle-Jena-Leipzig, Germany
Abstract
The coronavirus disease 2019 (COVID-19) pandemic has caused significant public health emergency globally. Although the clinical manifestation of COVID-19 is heterogeneous with flu-like symptoms to acute pneumonia and multiple organ failure, its risk, severity and mortality have been associated with diabetes and other non-communicable chronic diseases. Accumulated evidence from emerging epidemiological data has shown enormous global public health concern with hypothetical association existing between COVID-19 and diabetes. Possible mechanisms recently explored as underlying association between COVID-19 and diabetes are hyperglycemia, chronic inflammation, impairment of immune response, increased and prolonged coagulation activity and rapid pancreatic damage by SARS-CoV-2. Furthermore, the discontinuation of angiotensin receptor blockers or angiotensin-converting enzyme inhibitors (ACEI) in individuals with diabetes due to COVID-19 has not been scientifically concluded. The burden associated with COVID-19 and diabetes comorbidity may exacerbate this pandemic, especially in developing countries. However, early diagnosis, comprehension and management of these comorbidities may contribute to better outcomes, hence mitigating severe clinical complications and mortalities.
Keywords
COVID-19; SARS-CoV-2; Pandemic; Diabetes; Global Health
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