Correlation Between Anti Mullerian Hormone Level and Antral Follicle Count Using Three-Dimensional Ultrasound in Cases of Recurrent Spontaneous Abortion
El-Sheikha, K., Sedek, A., Mohammed, I., Hafez, A. (2018). Correlation Between Anti Mullerian Hormone Level and Antral Follicle Count Using Three-Dimensional Ultrasound in Cases of Recurrent Spontaneous Abortion. EKB Journal Management System, 73(4), 6392-6400. doi: 10.21608/ejhm.2018.15089
Khaled Zakaria El-Sheikha; Abd El Monsef Abd Elhamid Sedek; Ibrahim Hassan Mohammed; Ahmed Mohamed Hussein Hafez. "Correlation Between Anti Mullerian Hormone Level and Antral Follicle Count Using Three-Dimensional Ultrasound in Cases of Recurrent Spontaneous Abortion". EKB Journal Management System, 73, 4, 2018, 6392-6400. doi: 10.21608/ejhm.2018.15089
El-Sheikha, K., Sedek, A., Mohammed, I., Hafez, A. (2018). 'Correlation Between Anti Mullerian Hormone Level and Antral Follicle Count Using Three-Dimensional Ultrasound in Cases of Recurrent Spontaneous Abortion', EKB Journal Management System, 73(4), pp. 6392-6400. doi: 10.21608/ejhm.2018.15089
El-Sheikha, K., Sedek, A., Mohammed, I., Hafez, A. Correlation Between Anti Mullerian Hormone Level and Antral Follicle Count Using Three-Dimensional Ultrasound in Cases of Recurrent Spontaneous Abortion. EKB Journal Management System, 2018; 73(4): 6392-6400. doi: 10.21608/ejhm.2018.15089

Correlation Between Anti Mullerian Hormone Level and Antral Follicle Count Using Three-Dimensional Ultrasound in Cases of Recurrent Spontaneous Abortion

The Egyptian Journal of Hospital Medicine
Article 3, Volume 73, Issue 4, October 2018, Page 6392-6400  XML PDF (345.04 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2018.15089
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Authors
Khaled Zakaria El-Sheikha1; Abd El Monsef Abd Elhamid Sedek1; Ibrahim Hassan Mohammed2; Ahmed Mohamed Hussein Hafez email 1
1Obstetrics & Gynecology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
2Biochemistry Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
Abstract
Background: abortion is one of the most common complications of pregnancy, occurring in 10–15% of pregnant women, whiles recurrent spontaneous abortion, rate of 2–5%, is defined as ≥ 3 spontaneous abortions.
Aim of the Work: was totry to find relationship between serum AMH concentration which represent ovarian reserve, Antral Follicular count and any pelvic Structural abnormality using 3D ultrasound in assessment cases with spontaneous recurrent abortion.
Patients and Methods: A multicenter, randomized trial included 100 women who were divided into 2 groups; Group 1, included 50 patients with ≥ 3 recurrent abortions and Group 2, included 50 parous women with regular menstrual cycles and having one or more living child without any history of pregnancy loss or pelvic structural abnormality. Every subject was subjected to assessing hormonal profile including anti-müllerian hormone (AMH) and Transvaginal ultrasonography.
Results: AMH was found to have negative correlation with age, number of abortions, FSH and LH.
Conclusion: It could be concluded that Anti-Müllerian hormone is the best indicator of ovarian reserve with a high sensitivity and specificity, so ovarian reserve of women with recurrent spontaneous abortions is not defective.
Keywords
Anti Mullerian Hormone Level; Antral Follicle Count; three-dimensional ultrasound; Recurrent spontaneous abortion
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