Antiviral Activities and Phytochemical Constituents of Egyptian Marine Seaweeds (CystoseiraMyrica(S.G. Gmelin) C. Agardh and Ulva Lactuca Linnaeus) Aqueous Extract | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 17, Volume 64, Issue 1, July 2016, Page 422-429 PDF (609.06 K) | ||||
Document Type: Original Article | ||||
DOI: 10.12816/0029034 | ||||
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Authors | ||||
Shaimaa Ashour Abdel-Latif Zaid1; Nermine Nasr El-Din Hamed2; Kouka Saad El-Din Abdel-Wahab3; Enas Kamal Abo El-Magd3; Rawheya Abdel-Latif Salah El-Din2 | ||||
1Microbiologist at Chemistry Administration,Ministry of Commerce and Industry | ||||
2Botany and Microbiology Department, Faculty of Science for Girls, Al-Azhar University | ||||
3Microbiology Department, Faculty of Medicine for Girls, Al-Azhar University | ||||
Abstract | ||||
Background: some natural and synthetic compounds can prevent, suppress, or reverse the progression of virus infection. Natural products have proven to be the most effective in terms of their ability to act as an antiviral. In the present study, the antiviral potentiality of the bioactive compounds derived from aqueous extract of two Egyptian marine seaweed species (Cystoseiramyrica and Ulva lactuca)were assessed on different viruses. Materials and methods:these two species were collected from Hurghada at the Red Sea and Al-Agami area in Alexandria Mediterranean Sea, Egypt.The assay of cytotoxicity and antiviral activity by MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenlytetrezolium bromide] and by neutralization methods were conducted. Results:these two species have a bioactive compound affected hepatitis A virus (HAV-H10), Coxsackie B4 virus,herpes simplex virus types-1 (HSV-1) and type2 (HSV-2), grow and cytopathic effect (CPE) in Vero cells. | ||||
Keywords | ||||
antivirus; Marine seaweed; Cystoseiramyrica; Ulva lactuca; Hurghada; Red Sea; Al-Agami; alexandria; Egypt | ||||
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