Clinico-Hematologic Profile of Chronic Lymphocytic Leukemia inEgypt: A Three-Center Experience | ||||
| The Medical Journal of Cairo University | ||||
| Article 2, Volume 89, March, March 2021, Page 9-17 PDF (753.36 K) | ||||
| DOI: 10.21608/mjcu.2021.152005 | ||||
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| Authors | ||||
| SABRY A. SHOEIB, M.D.; AYMAN F. ARAFA, M.D.; ATEF M. TAHA, M.D.; MOHAMED A. ABDEL HAFEZ, M.D.; MAHMOUD A. ELREFY, M.Sc. | ||||
| The Department of Internal Medicine* and Hematology**,*** Department, Faculty of Medicine, Menoufia*, Zagazeg** andTanta*** Universities, Shebeen Elkom, Menoufia, Egypt | ||||
| Abstract | ||||
| AbstractBackground: Chronic lymphocytic leukemia is a malig-nancy of CD5+ B cells that is characterized by the accumulationof small, mature-appearing neoplastic lymphocytes in theblood, bone marrow and secondary lymphoid tissues, resultingin lymphocytosis, leukemic cell infiltration of the bone marrow,lymphadenopathy and splenomegaly.Aim of Study: Our objective was to analyse clinical,haematological, immunophenotypic and cytogenetic profilesof Chronic Lymhocytic Leukemia (CLL) in Egypt.Patients and Methods: This retrospective study involvedone hundred and twenty adult CLL patients diagnosed accord-ing to International Workshop on Chronic LymphocyticLeukemia (IW-CLL) from January 2011 to December 2019.Data were collected and statistically analysed.Results: Chronic lymphocytic leukemia is a disease ofelderly and may have an association hepatitis C virus. Thestudy showed that mean of age of CLL patients was 61.03 (±9.9), 42 (35%) of patients were positive for hepatitis Cantibody.Conclusion: Chronic lymphocytic leukemia is adiseaseof elderly, there may be an association between hepatitis Cvirus and development of chronic lymphocytic leukemia. | ||||
| Keywords | ||||
| Chronic lymphocytic leukemia; Clinical profile; Hematological profile | ||||
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