Routine Early Coronary Angioplasty versus Ischaemia-Guided Coronary Angioplasty after Successful Thrombolysis in Patients with Acute Anterior STEMI
Nassar, A., Hanna, H., Mohamed, H., Andrawes, A., Ragy, H. (2018). Routine Early Coronary Angioplasty versus Ischaemia-Guided Coronary Angioplasty after Successful Thrombolysis in Patients with Acute Anterior STEMI. EKB Journal Management System, 63(1), 213-216. doi: 10.12816/0023849
Ahmed Ibrahim Nassar; Hany Fouad Hanna; Haytham Galal Mohamed; Amir Wadie Andrawes; Hany Ibrahim Ragy. "Routine Early Coronary Angioplasty versus Ischaemia-Guided Coronary Angioplasty after Successful Thrombolysis in Patients with Acute Anterior STEMI". EKB Journal Management System, 63, 1, 2018, 213-216. doi: 10.12816/0023849
Nassar, A., Hanna, H., Mohamed, H., Andrawes, A., Ragy, H. (2018). 'Routine Early Coronary Angioplasty versus Ischaemia-Guided Coronary Angioplasty after Successful Thrombolysis in Patients with Acute Anterior STEMI', EKB Journal Management System, 63(1), pp. 213-216. doi: 10.12816/0023849
Nassar, A., Hanna, H., Mohamed, H., Andrawes, A., Ragy, H. Routine Early Coronary Angioplasty versus Ischaemia-Guided Coronary Angioplasty after Successful Thrombolysis in Patients with Acute Anterior STEMI. EKB Journal Management System, 2018; 63(1): 213-216. doi: 10.12816/0023849

Routine Early Coronary Angioplasty versus Ischaemia-Guided Coronary Angioplasty after Successful Thrombolysis in Patients with Acute Anterior STEMI

The Egyptian Journal of Hospital Medicine
Article 11, Volume 63, Issue 1, April 2016, Page 213-216  XML PDF (281.95 K)
Document Type: Original Article
DOI: 10.12816/0023849
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Authors
Ahmed Ibrahim Nassar1; Hany Fouad Hanna1; Haytham Galal Mohamed1; Amir Wadie Andrawes email 1; Hany Ibrahim Ragy2
1Cardiology department, Ain Shams university
2National heart institute
Abstract
Background: the potential benefits of routine early intervention after thrombolysis include prevention of re-infarction, recurrent ischemia, and reduction of the infarct size and mortality.
Aim of the work: the purpose of this study is to compare routine early coronary angioplasty in patients with acute anterior STEMI after successful thrombolysis versus ischaemia-guided coronary angioplastyas regards the occurrence of MACCE.
Study design: a total number of 100 patients with acute anterior STEMI received thrombolytic therapy and then were randomly assigned to either routine invasive strategy or ischemia based strategy based on risk stratification by stress myocardial perfusion scan done within 30 days of the onset of AMI with subsequent CA after demonstration of residual myocardial ischemia and or good viability.
Results: the cumulative incidence of MACCE including recurrent ischemia, stroke, MI, HF or mortality was significantly lower in theroutine early invasive strategy.
Conclusion: STEMI patients who cannot undergo timely primary PCI should receive prompt fibrinolysis followed by early routine invasive strategy.
 
Keywords
Pharmaco-invasive PCI
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