Left Ventricular Dysfunction in Prediabetic Patients: A review article

Elsenbsy, Mohamed A.; Sabra, Ahlam M.; Ali, Abdulla Eliaw Mohamed; Sayed, Gehad Osama Fawzy; Mahmoud, Hossam Eldin M.

doi:10.21608/svuijm.2021.63389.1088

	Left Ventricular Dysfunction in Prediabetic Patients: A review article
SVU-International Journal of Medical Sciences
Article 28, Volume 5, Issue 1, January 2022, Page 261-267 PDF (281.8 K)
Document Type: Reviews Articles.
DOI: 10.21608/svuijm.2021.63389.1088
View on SCiNiTO
Authors
Mohamed A. Elsenbsy¹; Ahlam M. Sabra²; Abdulla Eliaw Mohamed Ali ³; Gehad Osama Fawzy Sayed ²; Hossam Eldin M. Mahmoud²
¹Department of Internal Medicine, Faculty of Medicine, South Valley University, Qena, Egypt & Internal Medicine Department ,Arabian Gulf University(AGU),Bahrain
²Department of Internal Medicine, Faculty of Medicine, South Valley University, Qena, Egypt.
³Department of Clinical Pathology, Faculty of Medicine, South Valley University, Qena, Egypt.
Abstract
Background: Prediabetes is a common condition that indicates a state between normal glucose metabolism and diabetes. This is considered a dangerous condition because of the high risk of developing diabetes. A recent study in Europe shows that visually impaired fasting increases glucose and impaired glucose tolerance. prevalence of impaired fasting glucose (IFG) levels range from approximately 3%to 5% in the 20 -44 age group and approximately 20% to 30% in the 65-74 age group. Evidence suggesting a link between the risk of neuropathy, nephropathy, early retinopathy, and macrovascular disease and prediabetes. Prediabetes is associated with a 20% increased risk of cardiovascular disease compared to normoglycemic individuals. Several studies have established systolic and diastolic left ventricular dysfunction in prediabetic patients. We aimed to highlight left ventricular dysfunction in Prediabetic patients and to describe the possible underlying mechanisms of this association. Conclusion : There is a significant association between left ventricular systolic and diastolic dysfunction and prediabetes. The defects underlying prediabetes which include insulin resistance, metabolic syndrome, dyslipidemia, and inflammation, have been implicated to predispose diabetic patients to increased risk of developing ventricular dysfunction.
Keywords
Prediabetes; left ventricular dysfunction, echocardiography


Statistics Article View: 223 PDF Download: 160