Physiological and Histological Studies on The Heart of Male Albino Rats Exposed to Electromagnetic Field and The Protective Role of Silymarin and/orVitamin E.
Zahkouk, S., El-Gendy, A., Eid, F., El-Tahway, N., El-Shamy, S. (2015). Physiological and Histological Studies on The Heart of Male Albino Rats Exposed to Electromagnetic Field and The Protective Role of Silymarin and/orVitamin E.. EKB Journal Management System, 58(1), 94-108. doi: 10.12816/0009364
Samir,A. Zahkouk; Ahkam M El-Gendy; Fatma A. Eid; Nomaan, A. El-Tahway; Sawsan A. El-Shamy. "Physiological and Histological Studies on The Heart of Male Albino Rats Exposed to Electromagnetic Field and The Protective Role of Silymarin and/orVitamin E.". EKB Journal Management System, 58, 1, 2015, 94-108. doi: 10.12816/0009364
Zahkouk, S., El-Gendy, A., Eid, F., El-Tahway, N., El-Shamy, S. (2015). 'Physiological and Histological Studies on The Heart of Male Albino Rats Exposed to Electromagnetic Field and The Protective Role of Silymarin and/orVitamin E.', EKB Journal Management System, 58(1), pp. 94-108. doi: 10.12816/0009364
Zahkouk, S., El-Gendy, A., Eid, F., El-Tahway, N., El-Shamy, S. Physiological and Histological Studies on The Heart of Male Albino Rats Exposed to Electromagnetic Field and The Protective Role of Silymarin and/orVitamin E.. EKB Journal Management System, 2015; 58(1): 94-108. doi: 10.12816/0009364

Physiological and Histological Studies on The Heart of Male Albino Rats Exposed to Electromagnetic Field and The Protective Role of Silymarin and/orVitamin E.

The Egyptian Journal of Hospital Medicine
Article 11, Volume 58, Issue 1, January 2015, Page 94-108  XML PDF (792.61 K)
Document Type: Original Article
DOI: 10.12816/0009364
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Authors
Samir,A. Zahkouk1; Ahkam M El-Gendy1; Fatma A. Eid1; Nomaan, A. El-Tahway2; Sawsan A. El-Shamy2
1Al-AzharUniversity,Faculty of Science,Zoology Department
2Misr University For Science and Technology
Abstract
Aim of the work:This study aimed to determine the ameliorative effect of silymarin (SIL) and\or vitamin E (Vit.E) against changes induced by mobile phone radiation in the heart of male albino rats. Matrerial and methods:Total of 48 adult male albino rats were assigned for this study. The 1st group served as control (n=6), the 2nd group exposed to mobile phone generator radiation (900MHz) for 2hr/day 3days/week for two months, 3rd group (+ve control) supplemented with SIL, 4th group (+ve control) supplemented with Vit. E, 5th group (+ve control) supplemented with SIL and Vit.E, 6th group: exposed group supplemented with SIL, 7th group: exposed group supplemented with Vit.E and 8th group exposed group supplemented with SIL and Vit.E. Physiological ,histopathological and histochemical changes were studied.Results: Exposure to mobile phone causes increases in activities of CPK, CK-MB and LDH enzymes in serum and heart tissue and oxidative stress markers (MDA and H2O2),while antioxidants (CAT and GSH) were decreased in the heart tissue. Sodium (Na) and calcium (Ca) levels were decreased While, K level showed non-significant change in serum. Numerous histopathological changes were detected in the heart tissue of rats of the irradiated group with altered collagen fibres, polysaccharides  in the cardiac muscle fibres of the exposed group. These changes manifested good amelioration in the exposed groups that supplemented with SIL and/or Vit.E.
Conclusion:Treatment of rats with SIL and/or Vit.E ameliorated the dangerous effect of mobile phone radiation occurred in the cardiac muscle fibres.
 
Keywords
Mobile phone radiation; albino rats; heart; Silymarin; Vitamin E
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