Angiopoietin-2 in ischemic cardiac patients
Abdelazim, A., Elsenbsy, M., Hassan, M., AK, M. (2023). Angiopoietin-2 in ischemic cardiac patients. EKB Journal Management System, 6(2), 482-488. doi: 10.21608/svuijm.2021.66008.1111
Ahmed Magdy Abdelazim; Mohammed Abdelrazek Elsenbsy; Mohammed H. Hassan; Mohammed AK. "Angiopoietin-2 in ischemic cardiac patients". EKB Journal Management System, 6, 2, 2023, 482-488. doi: 10.21608/svuijm.2021.66008.1111
Abdelazim, A., Elsenbsy, M., Hassan, M., AK, M. (2023). 'Angiopoietin-2 in ischemic cardiac patients', EKB Journal Management System, 6(2), pp. 482-488. doi: 10.21608/svuijm.2021.66008.1111
Abdelazim, A., Elsenbsy, M., Hassan, M., AK, M. Angiopoietin-2 in ischemic cardiac patients. EKB Journal Management System, 2023; 6(2): 482-488. doi: 10.21608/svuijm.2021.66008.1111

Angiopoietin-2 in ischemic cardiac patients

SVU-International Journal of Medical Sciences
Article 46, Volume 6, Issue 2, July 2023, Page 482-488  XML PDF (315.39 K)
Document Type: Reviews Articles.
DOI: 10.21608/svuijm.2021.66008.1111
View on SCiNiTO View on SCiNiTO
Authors
Ahmed Magdy Abdelazim email 1; Mohammed Abdelrazek Elsenbsy2; Mohammed H. Hassanorcid 3; Mohammed AK4
1Department of Internal Medicine, Faculty of Medicine, South Valley University, Qena, 83523 Egypt.
2Department of Internal Medicine, Faculty of Medicine, South Valley University, Qena, 83523 Egypt.; Internal Medicine Department ,Arabian Gulf University(AGU),Bahrain.
3Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, South Valley University, Qena, Egypt
4Cardiology Division of Internal Medicine Department, South Valley University Hospital, Faculty of Medicine, South Valley University, Qena, 83523 Egypt.
Abstract
Background: Coronary artery disease (CAD) is the most common cause of death globally according to WHO. Its known that ischemia and cardiac dysfunction promotes the angiogenesis and new vessel formation to compensate for the decreased blood supply through the diseased arteries.Angiopoietin-2(Ang-2) along with several other growth factors are responsible for the process of new vessel formation. Many patients have some degree of renal insufficiency post PCI mainly due to contrast media and are associated with rise in the serum Ang-2 level. Ang-2 is found to be decreased post PCI with the restoration of the normal blood flow. Many clinical trials relate the Ang-2 with the severity of CAD and renal function.
Objectives: Highlight the serum levels of Ang-2 pre and post PCI and its validity to be used to diagnose and predict severity of CAD.
Methods: We have searched literatures in PubMed, google scholar, Egyptian bank of knowledge and science direct.
Conclusion: In this review we emphasize that Ang-2 is found to be an important marker for diagnosis and prognosis of CAD and is closely related to renal functions in ischemic cardiac patients candidate for PCI.
Keywords
Percutaneous coronary intervention (PCI); contrast induced nephropathy (CIN); angiopoietin-2(Ang-2)
Statistics
Article View: 325
PDF Download: 83