Effect of Ginger Extract Consumption on levels of blood Glucose, Lipid Profile and Kidney Functions in Alloxan Induced-Diabetic Rats. | ||||
| Egyptian Academic Journal of Biological Sciences. A, Entomology | ||||
| Article 17, Volume 2, Issue 1, June 2009, Page 153-162 PDF (551.91 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/eajbsa.2009.15515 | ||||
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| Authors | ||||
| Abd-Elraheem A. Elshater; Muhammad M. A. Salman; Mahrous M. A. Moussa | ||||
| South Valley University, Faculty of Science, Zoology Department | ||||
| Abstract | ||||
| In recent years, ginger has become a subject of interest because of its beneficial effects on human health. The purpose of the present study was to investigate the effects of daily oral administration of ginger extract for 6 weeks on plasma glucose, lipid profile and kidney functions in alloxan-induced diabetic rats to show the ameliorating and partly curative effects in alloxan induced-diabetic rats (150 mg/kg i.p.(Intrapretonial). Rats (130-150gm) were divided into 4 groups; normal control rats, diabetic control rats, diabetic rats post-treated with ginger and diabetic rats pretreated with ginger. Ginger extract was administered orally for 6 weeks to post-treated and pre-treated rats, and they were compared with the normal and diabetic groups, respectively. Plasma glucose was reduced significantly in both post-treated and pre-treated groups. The post-treatment with ginger extract reduced plasma cholesterol, triglyceride and LDL-cholesterol, but during the pre-treatment with ginger extract produced insignificant change only in plasma triglyceride level. The plasma HDL-cholesterol was significantly increased in post-treated and pre-treated groups. The plasma creatinine, urea and uric acid levels were significantly reduced in post-treated group; also in pre-treated group, they were reduced but urea level statistically did not change. It is concluded that the consumption of ginger produced a significant hypoglycemic effect in diabetic rats. In addition, ginger is capable of improving hyperlipidemia and the impaired kidney functions in alloxan-induced diabetic rats | ||||
| Keywords | ||||
| Ginger; Kidney function; glucose; plasma; lipids; alloxan; Rats; diabetic | ||||
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