The value of urine Soluble Triggering Receptor expressed on Myloid cell-1 in early diagnosis of Sepsis associated Acute Kidney Injury | ||||
Benha Medical Journal | ||||
Article 31, Volume 38, Issue 1, April 2021, Page 380-394 PDF (798.19 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bmfj.2021.56361.1367 | ||||
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Authors | ||||
Mohamed Ahmed Elbaz; Effat Hussein Assar; Heba Mohamed Sarhan; Ayat Hashim | ||||
Pediatric department;faculty of medicine;Benha University;Qalyubia | ||||
Abstract | ||||
Introduction We explored the diagnostic value of a urine soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) for early sepsis identification, severity and prognosis assessment, and for secondary acute kidney injury (AKI). We compared this with white blood cell (WBC) counts, serum C-reactive protein (CRP), urine output, creatinine clearance (CCr), serum creatinine (SCr), and blood urea nitrogen (BUN). Methods This case control study will be conducted on 50 critically ill children with sepsis admitted to PICU and 20 healthy children as control group. Study group will be classified as follows : I. Patients : - group (A) : Septic patients with AKI - group (B) : Septic patients without AKI II. Control group (20) with the same age&sex Results for urine Strem-1,CBC,CRB and S.Creatinine were recorded on day 1 Results There were no significant differences between all groups as regard age & gender. P values were 0.43 & 0.709 respectively sTREM-1 showed overall significant difference between all groups (P value | ||||
Keywords | ||||
urine soluble triggering receptor expressed on myeloid cells-1(sTREM-1); sepsis; prognosis; acute kidney injury (AKI) | ||||
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