SYNTHESIS AND PHARMACOLOGICAL SCREENING OF CERTAIN IMIDAZOQUINAZOLONE DERIVATIVES | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 2, Volume 31, Issue 1, June 2008, Page 29-48 PDF (393.51 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.2008.156596 | ||||
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Authors | ||||
Fatma A. Ragab; Hassanein H. Hassanein; Enayat I. Ali; Hanan H. Georgey | ||||
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Egypt | ||||
Abstract | ||||
Certain imidazoquinazolin-5(4H)-one derivatives have been synthesized by replacement of the 4-amino group compound I with different moieties of expected biological activity. Representative example of the synthesized compounds were tested for their anti-inflammatory, analgesic, antipyretic and anticonvulsant activities. Certain derivatives showed activities higher than that of the reference drugs. | ||||
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