Relation between Zinc Level and One Year Mortality among Elderly Patients with Heart Failure
Abdel-Salam, N., Aly, W., Hamza, S., Mortagy, A., Fahmy, H. (2014). Relation between Zinc Level and One Year Mortality among Elderly Patients with Heart Failure. EKB Journal Management System, 54(1), 11-14. doi: 10.12816/0002425
Nora Abdel-Khalek Abdel-Salam; Walaa Wessam Aly; Sarah Ahmed Hamza; Ahmed Kamel Mortagy; Hossam Mosfata Fahmy. "Relation between Zinc Level and One Year Mortality among Elderly Patients with Heart Failure". EKB Journal Management System, 54, 1, 2014, 11-14. doi: 10.12816/0002425
Abdel-Salam, N., Aly, W., Hamza, S., Mortagy, A., Fahmy, H. (2014). 'Relation between Zinc Level and One Year Mortality among Elderly Patients with Heart Failure', EKB Journal Management System, 54(1), pp. 11-14. doi: 10.12816/0002425
Abdel-Salam, N., Aly, W., Hamza, S., Mortagy, A., Fahmy, H. Relation between Zinc Level and One Year Mortality among Elderly Patients with Heart Failure. EKB Journal Management System, 2014; 54(1): 11-14. doi: 10.12816/0002425

Relation between Zinc Level and One Year Mortality among Elderly Patients with Heart Failure

The Egyptian Journal of Hospital Medicine
Article 2, Volume 54, Issue 1, January 2014, Page 11-14  XML PDF (236.87 K)
Document Type: Original Article
DOI: 10.12816/0002425
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Authors
Nora Abdel-Khalek Abdel-Salam1; Walaa Wessam Aly1; Sarah Ahmed Hamza1; Ahmed Kamel Mortagy1; Hossam Mosfata Fahmy2
1Geriatric Medicine Faculty of Medicine - Ain Shams University
2Clinical Pathology Faculty of Medicine - Ain Shams University
Abstract
Background: Zinc (Zn) deficiency in endothelial cells potentiates the inflammatory response mediated by certain lipids and cytokines, possibly via mechanisms associated with increased cellular oxidative stress.
Objectives: To assess the relation between zinc level and one year mortality among elderly patients with heart failure.
Patients and Methods: Serum zinc level was measured in 100 elderly patients with heart failure diagnosed by Criteria of New York Heart Association (NYHA). Patients were followed by telephone for one year to assess relation between Zinc level and one year mortality among elderly patients with heart failure. Results: Higher mortality percentage was found among patients with high level of zinc but there was no statistical significant difference. (P-value >0.05). And non significant relation was found between mean level of zinc and mortality, between age and Zn, and between  Ejection Fraction (EF) and Zn. Zn level was lower among patients with EF >45 but the difference was not significant (P-value >0.05). Conclusion: Patients who had high level of zinc had greater risk for mortality. Zn level was lower among patients with EF >45 but the difference was not significant and the least mean of zinc was among patients with left ventricular (LV) systolic dysfunction.
 
Keywords
zinc; mortality; elderly patients; Heart failure
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