The Effect of Lupinus Albus (Termis) and Hyphaene Thebaica (Doum) on Some Biochemical Parameters in Streptozotocin-Induced Diabetic Rats
Tohamy, A., Mohammed, R., Abdalla, M., Ibrahim, A., Mahran, K. (2013). The Effect of Lupinus Albus (Termis) and Hyphaene Thebaica (Doum) on Some Biochemical Parameters in Streptozotocin-Induced Diabetic Rats. EKB Journal Management System, 53(1), 789-794. doi: 10.12816/0001640
Amany A Tohamy; Rasha S Mohammed; Mohga S Abdalla; Adel K Ibrahim; Khaled F Mahran. "The Effect of Lupinus Albus (Termis) and Hyphaene Thebaica (Doum) on Some Biochemical Parameters in Streptozotocin-Induced Diabetic Rats". EKB Journal Management System, 53, 1, 2013, 789-794. doi: 10.12816/0001640
Tohamy, A., Mohammed, R., Abdalla, M., Ibrahim, A., Mahran, K. (2013). 'The Effect of Lupinus Albus (Termis) and Hyphaene Thebaica (Doum) on Some Biochemical Parameters in Streptozotocin-Induced Diabetic Rats', EKB Journal Management System, 53(1), pp. 789-794. doi: 10.12816/0001640
Tohamy, A., Mohammed, R., Abdalla, M., Ibrahim, A., Mahran, K. The Effect of Lupinus Albus (Termis) and Hyphaene Thebaica (Doum) on Some Biochemical Parameters in Streptozotocin-Induced Diabetic Rats. EKB Journal Management System, 2013; 53(1): 789-794. doi: 10.12816/0001640

The Effect of Lupinus Albus (Termis) and Hyphaene Thebaica (Doum) on Some Biochemical Parameters in Streptozotocin-Induced Diabetic Rats

The Egyptian Journal of Hospital Medicine
Article 5, Volume 53, Issue 1, October 2013, Page 789-794  XML PDF (312.48 K)
Document Type: Original Article
DOI: 10.12816/0001640
View on SCiNiTO View on SCiNiTO
Authors
Amany A Tohamy1; Rasha S Mohammed1; Mohga S Abdalla2; Adel K Ibrahim3; Khaled F Mahran3
1Department of zoology and entomology, Faculty of science, Helwan University
2Department of chemistry, Faculty of science, Helwan University
3Department of clinical pathology, Veterinary Medicine, Cairo University.
Abstract
Background: Several plants have been used as dietary adjuvant and in treating the number of diseases because of their perceived effectiveness, minimal side effects in clinical experience and relatively low costs.The present study focuses on evaluating the effect of Lupinus albus (termis) and Hyphaene thebaica (doum) on STZ-diabetic rats at the level of some biochemical parameters Material and methods: STZ was injected intraperitoneally at a single dose of 50 mg/kg to induce diabetes. Termis seeds suspension (75 mg/100 g b.wt.) was daily orally administered. Doum palm fruit suspension was daily orally administered (1g/kg b.wt.) and also gliclazide (reference drug) was administered of a dose equivalent to the therapeutic dose of rat. After four weeks of administration, blood samples were collected for biochemical measurement. Results: Blood glucose level was significantly increased. Diabetes increased serum total lipids, cholesterol, triglycerides and LDL but serum HDL wasdecreased. Also activities of serum enzymes ASAT, ALAT, ALP, GGT and LDH were elevated. However, L. albus and H. thebaica improved the level of mostly all biochemical parameters.  
Conclusion:  It is concluded that termis and doum may be dietary adjuvant in reducing the  harmful of diabetes.
 
 
 
Keywords
Lupinus albus Hyphaene thebaica; Gliclazide; streptozotocin; diabetic rat
Statistics
Article View: 219
PDF Download: 624