EVALUATION OF BONE REGENERATION OF MAXILLARY CYSTIC DEFECT GRAFTED WITH PUERARIN WITH CALCIUM SULPHATE GRANULES VERSUS CALCIUM SULPHATE GRANULES AS A SOLOGRAFT: A RANDOMIZED CONTROLLED CLINICAL TRIAL | ||||
| Egyptian Dental Journal | ||||
| Article 9, Volume 67, Issue 2, April 2021, Page 1147-1156 PDF (3.27 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/edj.2021.65551.1533 | ||||
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| Authors | ||||
Saleh Bakry  ; Hesham Fattouh
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| Associate Professor Oral Surgery Department, Faculty of Dentistry, Cairo University, Egypt | ||||
| Abstract | ||||
| Aim: The aim of this study was to evaluate bone regeneration of maxillary cystic defect grafted with puerarin with calcium sulphate granules versus calcium sulphate granules as a solograft. Materials and Methods: This was a randomized controlled clinical trial conducted on 20 patients suffering from maxillary cystic lesions with size more than 3 cm2 indicated for enucleation without the need for resection or plate reconstruction. In the first group (A): Bony cavities were grafted by Puerarin mixed with hemihydrated calcium sulphate bone graft granules, while in the second group (B): The bony cavities were grafted by hemihydrated calcium sulphate bone graft granules only. All patients were followed up for 6 months recording the progress of the healing both clinically and radiographically via CBCT. Results: Surgeries went uneventful in patients of both groups. No notable complications occurred during the surgical procedures and the healing period of the two groups. Radiographic results after 6 months showed that there was a significant decrease in cyst volume in the purerein group compared to the other group. Conclusions: Puerarin is a promising graft material with probably an osteoinductive role, an issue that needs more researches to optimize its use and to understand its bone forming mechanism. | ||||
| Keywords | ||||
| Puerarin; calcium sulphate; cyst enucleation; graft material | ||||
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