Reosseointegration of bone defect surrounding dental implant associated with periimplantitis using Nanobone with or without simvastatin: A six month randomised controlled clinical trial. | ||||
| Egyptian Dental Journal | ||||
| Article 5, Volume 67, Issue 2 - Serial Number 3, April 2021, Page 1241-1250 PDF (918.94 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/edj.2021.56962.1443 | ||||
 View on SCiNiTO | ||||
| Author | ||||
Omar Soliman  
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| Lecturer of Oral Medicine , Periodontoloy and Oral Diagnosis، Faculty of Dentistry, South Valley University | ||||
| Abstract | ||||
| Abstract: Objectives: The aim of the study was evaluating the effect of adding simvastatin to synthetic bone substitute on the regenerative surgical treatment of bone defects associated with periimplantitis in a six months randomized controlled clinical trial. Material & Methods: 30 patients diagnosed with periimplantitis divided in two groups, group I treated by using synthetic bone substitute (Nanobone), group II treated by using Nanobone with simvastatin. Clinical evaluation was the measurements for probing pocket depth (PPD), clinical attachment level (CAL), plaque index (PI), modified sulcus bleeding index (mSBI) and mucosal recession. Radiographic bone fill was evaluated at baseline and after six months. Results: The results for both treatment groups showed significant reductions obtained in the mean PPD, CAL and mSBI at six months postoperatively when compared to baseline values , on the other-side no statistically significant difference was observed for the mean PI and MR. The mean of bon fill in group II was better than that of group I and this results was statistically significant (P < 0.05). Conclusions: The two regenerative approaches produced significant improvements in both clinical and radiographic assessments, but adding simvastatin to Nanobone produce better results in terms of bone fill. | ||||
| Keywords | ||||
| Nanobone; simvastatin; periimplantitis; surgical treatment | ||||
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