Evaluation of 2-methacryloyloxyethyl phosphorylcholine polymer coated polyamide denture base material: Surface Roughness and Candida Albicans adhesion. | ||||
Egyptian Dental Journal | ||||
Article 6, Volume 67, Issue 2 - Serial Number 4, April 2021, Page 1391-1398 PDF (991.53 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/edj.2021.50708.1353 | ||||
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Authors | ||||
tayseer maaly 1; Eman MOHAMED 2 | ||||
1Lecturer, Dental Biomaterials Department, Faculty of Dentistry, Zagazig University. | ||||
2Dental Prosthodontics Department, Faculty of Dentistry, Zagazig University | ||||
Abstract | ||||
Purpose: To evaluate Candida albicans adhesion and the surface roughness of polyamide denture base material coated with various concentrations of 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer. Materials and Methods: A total of 80 disks polyamide resin specimens were fabricated and divided into 4 groups (n = 20/group). Surfaces of the specimens in three groups were coated with MPC in different concentrations (0.25 mol/L; 0.50 mol/L and 0.75 mol/L), while uncoated specimens were used as control. Surface roughness (SR) was evaluated using a profilometer. Specimens were incubated with C. albicans for 18 h and the number of adhered cells was determined. Statistically, the following tests were done: analysis of variance, Pearson correlation coefficient test, post hoc Tukey test. Results: Upon PMPC coating, surface roughness values were decreased, with a significant difference between different groups. A statistically significant decrease was observed in C. albicans adhesion in parallel with the increase in the MPC polymer concentration. There was no significant difference between 0.50 mol/L and 0.75 mol/L groups in terms of adhesion. These findings indicated that graft polymerization of MPC on polyamide denture base material reduces the adhesion of C. albicans, and may be evaluated as a coating for prevention of denture stomatitis. Conclusion: Coating of removable prosthesis with 0.75 mol/L MPC is suitable to reduce C. albicans adhesion on polyamide denture base. | ||||
Keywords | ||||
: Polyamide denture base; MPC; candida adhesion; surface roughness | ||||
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