Assessment of Oral Cellular proliferative activity among Toombak Dipper in Al-Obeyed City, Sudan | ||||
Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology | ||||
Article 13, Volume 6, Issue 2, December 2014, Page 107-113 PDF (540.45 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/eajbsc.2014.16037 | ||||
View on SCiNiTO | ||||
Authors | ||||
Awad Eljeed Abugooda Alobaid1; Ibrahim Bakhit Yousef Elemam1; Mohammed Abed Algader Alsheikh2; Abdalhafeez Osman Mahmud3; Hussain Gadelkarim Ahmed3 | ||||
1Department of Histopathology and Cytology, Medical Laboratory Sciences, Al-yarmouk College, Khartoum, Sudan. | ||||
2Department of Histopathology and Cytology, Medical Laboratory Sciences, Al-yarmouk College, Khartoum, Sudan | ||||
3Department of Pathology, College of Medicine, University of Hail, KSA | ||||
Abstract | ||||
Background: Many factors have been identified as important causative agents that responsible for the development of oral precancerous and cancerous lesions. In Sudan, Toombak have been identified as a major risk factor. Therefore, the aim of this study was to assess the cellular proliferative activity that associated with Toombak use. Methodology: In this study 75 apparently healthy individuals were selected for this study, of whom 50 were currently Toombak users (cases) and 25 were non-Toombak users (controls), Pap. Method and Silver technique were used for the staining of oral smears. Results: Cytological atypia was identified in 10 cases and 4 controls. The mean count NORs count was 4.6 in cases and 2.2 in controls. Conclusion: Toombak is a major risk for occurrence of cellular proliferative activity features that may progress in to oral precancerous or cancerous lesions. | ||||
Keywords | ||||
Toombak; Cytological atypia; oral cancer; Al-Obeyed | ||||
Statistics Article View: 215 PDF Download: 301 |
||||