Antimicrobial Activity of the Crude Ethanolic Extract of Carrichtera annua DC. Collected from Sinai, Egypt | ||||
Records of Pharmaceutical and Biomedical Sciences | ||||
Article 6, Volume 5, Pharmacognosy-Microbiology - Serial Number 2, January 2021, Page 60-63 PDF (675.2 K) | ||||
Document Type: Short communications | ||||
DOI: 10.21608/rpbs.2021.61630.1093 | ||||
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Authors | ||||
Enas Eltamany 1; Jihan M. Badr2; Haidy A. Ahmed3; safwat abd elmaasode ahmed4 | ||||
1Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt; | ||||
2Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt | ||||
3Ismailia Health Affairs Directorate, Ismailia 41525, Egypt | ||||
4pharmacognosy department,faculty of pharmacy,Suez canal university,Ismailia,Egypt. | ||||
Abstract | ||||
Carrichtera annua a plant belonging to family Brassicaceae was selected to be evaluated for its antimicrobial activity against a number of microorganisms. The powdered plant was extracted with ethanol until exhaustion. The concentrated ethanol extract was tested against a number of fungi, gram positive and gram-negative bacteria. The results revealed that the extract showed a significant and promising activity towards Aspergillus fumigatus, Proteus vulgaris, Enterococcus faecalis and Staphylococcus aureus with inhibition zones equal 17, 15, 13 and 11 mm. respectively. However, it displayed a weak activity on Bacillus subtilis and Klebsiella pneumonia. In contrast, the extract was inactive against Candida albicans, Trichophyton rubrum, Bacillus cereus, Methicillin-Resistant Staphylococcus aureus (MRSA), Salmonella typhimurium, Escherichia coli and Pseudomonas aeruginosa. Additionally, the minimum inhibitory concentration (MIC) was determined and illustrated that, the most susceptible organisms to C. annua were Aspergillus fumigatus and Proteus vulgaris with MIC of 2.5 mg/mL and 5 mg/mL respectively. Therefore, C. annua could be considered as a promising source for effective antimicrobial agent. | ||||
Keywords | ||||
Carrichtera annua; Brassicaceae; antimicrobial activity | ||||
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