Evaluation of Some Biochemical Changes in Diabetic Patients
.El-desoky, M., Amin, A., .El-refai, M., Farid, R., Labib, A. (2018). Evaluation of Some Biochemical Changes in Diabetic Patients. EKB Journal Management System, 50(1), 150-155. doi: 10.21608/ejhm.2018.16084
M.A .El-desoky; A.E. Amin; M.O .El-refai; R.J. Farid; A.A. Labib. "Evaluation of Some Biochemical Changes in Diabetic Patients". EKB Journal Management System, 50, 1, 2018, 150-155. doi: 10.21608/ejhm.2018.16084
.El-desoky, M., Amin, A., .El-refai, M., Farid, R., Labib, A. (2018). 'Evaluation of Some Biochemical Changes in Diabetic Patients', EKB Journal Management System, 50(1), pp. 150-155. doi: 10.21608/ejhm.2018.16084
.El-desoky, M., Amin, A., .El-refai, M., Farid, R., Labib, A. Evaluation of Some Biochemical Changes in Diabetic Patients. EKB Journal Management System, 2018; 50(1): 150-155. doi: 10.21608/ejhm.2018.16084

Evaluation of Some Biochemical Changes in Diabetic Patients

The Egyptian Journal of Hospital Medicine
Article 13, Volume 50, Issue 1, January 2013, Page 150-155  XML PDF (284.48 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2018.16084
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Authors
M.A .El-desoky1; A.E. Amin1; M.O .El-refai1; R.J. Farid2; A.A. Labib3
1Department of Chemistry,Biochemistry Division, Faculty of Science, Cairo University.
2Department of Clinical Pathology, Faculty of Medicine, Cairo University
3M.Sc candidate, Faculty of Science, Cairo University
Abstract
Patients and  methods: The present study consisted of 50 subjects were classified into three groups ;
Group (GI) Control group consisted of 10 clinically healthy adult subjects of both sexes free from any liver , kidney or cardiovascular diseases .
Group (GII) diabetes mellitus type 1 consisted of 20 patients of both sexes.
Group (GIII) diabetes mellitus type 1 with nephropathy consisted of 20 patients of both sexes . All subjects were undergo to the following investigated parameters; Ascorbic acid (vitamin C) ,Catalase ,Total antioxidant capacity, Aldolase and  Pyruvate kinase enzyme.                                                         
Results: vitamins C, catalase, total antioxidant capacity enzymes were highly significant decreased (P < 0. 01) in  diabetes mellitus type 1 (GII)  and diabetes mellitus type 1 with  nephropathy (GIII)  when compared to the control group. Adolase activity washighly significant increased (P < 0. 01) in diabetes mellitus type 1 with  nephropathy (GIII) when compared to the control group . Pyruvate Kinase activitywashighly significant increased (P < 0. 01) in diabetes mellitus type 1 (GII) when compared to the control group .
Conclusion: The antioxidant  and enzymes can be used for follow up in patients  suffering from diabetes mellitus type 1   and predict other complications.
 
Keywords
Diabetes mellitus; diabeteic nephropathy; ascorbic acid; Catalase enzyme; Total Antioxidant Capacity; Aldolase enzyme and Pyruvate kinase enzyme
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