SATHESIS AND ANTITICROBIALEVALUATI0N OF CERTAIN NEW 1,2,4-TRIAZOLE AND p-AMINOBENZOIC ACID DERIVATIVES | ||||
Zagazig Journal of Pharmaceutical Sciences | ||||
Article 1, Volume 18, Issue 2, December 2009, Page 1-7 PDF (1.8 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/zjps.2009.162493 | ||||
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Authors | ||||
Mohamed Hussien ; Ali Ahmdy | ||||
Pharmaceutical Chemistry and Microbiology Department faculty of Pharmacy ,Cairo University. Cairo, Egypt. | ||||
Abstract | ||||
Different types of mycoses especially invasive mycoses caused by yeasts and molds. are a growing problem in healthcare Candida albicans is one of the most common opportunistic fungi responsible for these kinds of infections the most notable explanation for this increase is a rise in the number of immunocompromised patients owing to advances in transplantation, the emergence of AIDS and rise m the number of invasive surgical procedures. Conveniently accessible hydrazide derivatives of benzoic acid 1 were converted to new thiosemicarbazides. Triazoles and alkylthiotriazoles. The antibacterial and antifungal activities were determined .Some of the newly synthesized compounds showed weak corresponding activities. | ||||
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