A STUDY RF CORNEAL (NDOTHELIAL SPECULAR MICROSCOPY IN MIDDLE AGED PATIENTV WITH CATARACT | ||||
Egyptian Journal of Clinical Ophthalmology | ||||
Article 2, Volume 2, Issue 2, December 2019, Page 49-55 PDF (198.93 K) | ||||
Document Type: Original articles: include clinical trials, interventional research, Basic researches and clinically relevant laboratory investigations | ||||
DOI: 10.21608/ejco.2019.162983 | ||||
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Authors | ||||
Mohamed, N.; Mohamed, U.; Ismail, A.; Alsamman, A. | ||||
Ophthalmology dept., Faculty of Medicine, Sohag Univ., Sohag, Egypt. | ||||
Abstract | ||||
Purpose: To study the corneal endothelium by specular microscopy in middle aged patients with cataract. Methods: this is observational cross-sectional retrospective clinical study. It included 500 eyes of 500 patents (244 females and 256 males) with cataract whose ages were between 40 and 60 (mean, 51.99 ± 7.32) that accepted to participate in this study in Sohag ophthalmic investigation center from the period of September 2017 to November 2018. Noncontact Topcon specular microscopy (model SP-1S, Japan) was performed in the studied eyes. Endothelial cell density (ECD), coefficient of variation (CV) in cell size, hexagonality of cells (HEX), and number of cells (N) were measured. Results: ECD readings ranges from 2017-3931 with a mean of 2835.29 and SD of 476.01. The median of COV is 36 and the range lies between 23-91. The mean of HEX is 50.61 with SD of 9.85 while the median is 52. Number of corneal cells in the study group ranges from 97-457 cells with a mean of 158.39 cells and SD of 55.86, while the median is 145 cells. The results of the present study revealed that WKH PHDQRI endothelial cell density is 2835.29 ± 476.01 cell/mm2, coefficient of variation in cell size is 37.78 ± 9.60 %, hexagonality of cells is 50.16 ± 9.85 % and number of cell is 158.39 ± 55. 86 cells. Conclusion: Specular microscopy can provide a non invasive morphologic analysis of the corneal endothelial cell layer from subjects enrolled in clinical trials. | ||||
Keywords | ||||
Corneal endothelium; Specular microscopy; Cataract | ||||
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