Evaluation of the Efficacy of 1% Alendronate Gel as Adjunctive Treatment in Class II Furcation Defects (Clinical, Radiographic and Biochemical Study)
Edrees, M., Abd Elhafeez, D., Gaber, A. (2021). Evaluation of the Efficacy of 1% Alendronate Gel as Adjunctive Treatment in Class II Furcation Defects (Clinical, Radiographic and Biochemical Study). EKB Journal Management System, 4(1), 83-90. doi: 10.21608/aadj.2021.164196
mohamed F Edrees; Dalia H Abd Elhafeez; Ahmed H Gaber. "Evaluation of the Efficacy of 1% Alendronate Gel as Adjunctive Treatment in Class II Furcation Defects (Clinical, Radiographic and Biochemical Study)". EKB Journal Management System, 4, 1, 2021, 83-90. doi: 10.21608/aadj.2021.164196
Edrees, M., Abd Elhafeez, D., Gaber, A. (2021). 'Evaluation of the Efficacy of 1% Alendronate Gel as Adjunctive Treatment in Class II Furcation Defects (Clinical, Radiographic and Biochemical Study)', EKB Journal Management System, 4(1), pp. 83-90. doi: 10.21608/aadj.2021.164196
Edrees, M., Abd Elhafeez, D., Gaber, A. Evaluation of the Efficacy of 1% Alendronate Gel as Adjunctive Treatment in Class II Furcation Defects (Clinical, Radiographic and Biochemical Study). EKB Journal Management System, 2021; 4(1): 83-90. doi: 10.21608/aadj.2021.164196

Evaluation of the Efficacy of 1% Alendronate Gel as Adjunctive Treatment in Class II Furcation Defects (Clinical, Radiographic and Biochemical Study)

Al-Azhar Assiut Dental Journal
Article 11, Volume 4, Issue 1, April 2021, Page 83-90  XML PDF (1.29 MB)
Document Type: Original Article
DOI: 10.21608/aadj.2021.164196
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Authors
mohamed F Edrees email 1; Dalia H Abd Elhafeez2; Ahmed H Gaber3
1Department of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology, Faculty of dental medicine, (Assiut, boys), Al-Azhar University, Egypt.
2.Department of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology, Faculty of dental medicine, (Assiut, boys), Al-Azhar University, Egypt
3Department of Oral Pathology, Faculty of dental medicine, (Assiut, boys), Al-Azhar University, Egypt.
Abstract
Aim: This study was designed to evaluate the efficacy of 1% alendronate gel as an adjunctive therapy to scaling and root planing in the treatment of class II furcation defects. Subjects and method: Twenty-six patients with mandibular class II furcation involvement were selected from the out-patient clinic, Oral Medicine and Periodontology Department, Faculty of Dentistry, Al-Azhar University, Assiut Branch. They were divided into two equal groups. Group I received conventional periodontal therapy alone, while group II received conventional periodontal therapy combined with intra-furcal application of 1% alendronate gel as adjunctive therapy. All patients were evaluated clinically, radiographically as well as for RANKL level in GCF at base line, 3 and 6 months. Results: Both groups showed a high significant difference between base line and 6 months in all clinical parameters (PI, GI, VPD, CAL and HPD), radiographic parameters (bone density) and RANKL level in GCF. There was a statistical significant difference to group II when compared to group I in VPD and HPD at 6 months only and in CAL, bone density and RANKL level at 3 and 6 months. Conclusion: intra-furcal application of 1%Alendronate gel seemed an attractive effect as adjunctive therapy in improving the clinical, radiographic parameters and RANKL level in GCF in the treatment of class II furcation defects
Keywords
Alendronate gel; root planing; class II furcation; Adjunctive Treatment; RANKL level
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