Ex-vivo Antimalarial and in-vitro Biological Activities of newly synthesized Co(II) complex with Schiff base
VEERAVEL, C., K, R., S, B., SELVARANI, R. (2021). Ex-vivo Antimalarial and in-vitro Biological Activities of newly synthesized Co(II) complex with Schiff base. EKB Journal Management System, 64(8), 4191-4195. doi: 10.21608/ejchem.2021.55320.3166
C. VEERAVEL; Rajasekar K; Balasubramaniyan S; R. SELVARANI. "Ex-vivo Antimalarial and in-vitro Biological Activities of newly synthesized Co(II) complex with Schiff base". EKB Journal Management System, 64, 8, 2021, 4191-4195. doi: 10.21608/ejchem.2021.55320.3166
VEERAVEL, C., K, R., S, B., SELVARANI, R. (2021). 'Ex-vivo Antimalarial and in-vitro Biological Activities of newly synthesized Co(II) complex with Schiff base', EKB Journal Management System, 64(8), pp. 4191-4195. doi: 10.21608/ejchem.2021.55320.3166
VEERAVEL, C., K, R., S, B., SELVARANI, R. Ex-vivo Antimalarial and in-vitro Biological Activities of newly synthesized Co(II) complex with Schiff base. EKB Journal Management System, 2021; 64(8): 4191-4195. doi: 10.21608/ejchem.2021.55320.3166

Ex-vivo Antimalarial and in-vitro Biological Activities of newly synthesized Co(II) complex with Schiff base

Egyptian Journal of Chemistry
Article 24, Volume 64, Issue 8, August 2021, Page 4191-4195  XML PDF (531.97 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2021.55320.3166
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Authors
C. VEERAVEL email orcid 1; Rajasekar Korcid 2; Balasubramaniyan S3; R. SELVARANI1
1DEPARTMENT OF CHEMISTRY, GOVT ARTS COLLEGE, ARIYALUR-621713. TAMIL NADU, INDIA
2Department of Chemistry, Govt Arts College, Ariyalur, Tamil Nadu, India
3Department Of Chemistry, Govt Arts College, Tamil Nadu, India
Abstract
Abstract
The first-row transition metal complex of Schiff base has been synthesized and characterized based on physicochemical spectral and biochemical methods. The metal-ligand stoichiometry and molecular formula of the complex assessed by Elemental analysis and metal estimation-neutral, monomeric nature of the complex and paramagnetic nature also predict by the conductance and magnetic moment study. The octahedral environment around Co(II) and metal-imine bond as a whole predicted by atomic IR and Far-IR spectra. In-vitro antibacterial and antifungal activities of the Schiff base and its complexes compared with those for standard (Chloramphenicol & Fluconazole) by agar disc diffusion method. The Ex-vivo antimalarial activity of the Schiff base and its metal complex was found by using Plasmodium falciparum bacteria/fungal.
Keywords
Keywords: Cinnamaldehyde; Aniline; ligand; Conductance; Chloramphenicol; and Fluconazole
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