A Pd-Np/Ac‐Catalyzed Transfer-Hydrogenation of Mesityl Oxide to Methyl Isobutyl Ketone using Sodium Formate as Hydrogen Donor
Sumiarsa, D., Maharani, R., Zainuddin, A., Hidayat, A., Nurhilal, O. (2021). A Pd-Np/Ac‐Catalyzed Transfer-Hydrogenation of Mesityl Oxide to Methyl Isobutyl Ketone using Sodium Formate as Hydrogen Donor. EKB Journal Management System, 64(9), 4843-4847. doi: 10.21608/ejchem.2021.65929.3416
Dadan Sumiarsa; Rani Maharani; Achmad Zainuddin; Ace Tatang Hidayat; Otong Nurhilal. "A Pd-Np/Ac‐Catalyzed Transfer-Hydrogenation of Mesityl Oxide to Methyl Isobutyl Ketone using Sodium Formate as Hydrogen Donor". EKB Journal Management System, 64, 9, 2021, 4843-4847. doi: 10.21608/ejchem.2021.65929.3416
Sumiarsa, D., Maharani, R., Zainuddin, A., Hidayat, A., Nurhilal, O. (2021). 'A Pd-Np/Ac‐Catalyzed Transfer-Hydrogenation of Mesityl Oxide to Methyl Isobutyl Ketone using Sodium Formate as Hydrogen Donor', EKB Journal Management System, 64(9), pp. 4843-4847. doi: 10.21608/ejchem.2021.65929.3416
Sumiarsa, D., Maharani, R., Zainuddin, A., Hidayat, A., Nurhilal, O. A Pd-Np/Ac‐Catalyzed Transfer-Hydrogenation of Mesityl Oxide to Methyl Isobutyl Ketone using Sodium Formate as Hydrogen Donor. EKB Journal Management System, 2021; 64(9): 4843-4847. doi: 10.21608/ejchem.2021.65929.3416

A Pd-Np/Ac‐Catalyzed Transfer-Hydrogenation of Mesityl Oxide to Methyl Isobutyl Ketone using Sodium Formate as Hydrogen Donor

Egyptian Journal of Chemistry
Article 14, Volume 64, Issue 9, September 2021, Page 4843-4847  XML PDF (254.46 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2021.65929.3416
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Authors
Dadan Sumiarsa email 1; Rani Maharani2; Achmad Zainuddin2; Ace Tatang Hidayat2; Otong Nurhilal3
1Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Indonesia
2Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran
3Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran
Abstract
Methyl isobutyl ketone (MIBK) is an α,β-unsaturated carbonyl compound, which is often used as solvent and extractor for antibiotics in the pharmaceutical industry. One alternative to the synthesis of MIBK from mesityl oxide (MO) is through catalytic transfer hydrogenation (CTH) using various organic compounds as hydrogen donors in the presence of a catalyst. The purpose of this study was to synthesize MIBK from MO through the CTH reaction using sodium formate as the hydrogen donor and Pd nanoparticles deposited on the activated charcoal (Pd-NP/AC) as the catalyst. Based on the Gas Chromatography-Mass Spectrometry (GC-MS) analysis, the conversion value of MO was obtained in 97.3% and the yield of the MIBK formation was 10.5%. Meanwhile, the highest selectivity was obtained in 17% at 40° C. The results show that sodium formate can effectively be used to reduce MO into MIBK in the presence of Pd-NP/AC catalyst at 70° C for 5 hours.
Keywords
Transfer hydrogenation; hydrogen donor; methyl isobutyl ketone; mesityl oxide; Pd-NP/AC; sodium formate
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