CLINICO-SEROEPIDEMIOLOGICAL EVALUATION OF TOXOCARIASIS IN EGYPTIAN EPILEPTIC CHILDREN | ||||
Journal of the Egyptian Society of Parasitology | ||||
Article 14, Volume 51, Issue 1, April 2021, Page 107-112 PDF (693.13 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/jesp.2021.165948 | ||||
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Authors | ||||
WAEL A. ABOU-YAMAN1; GAMAL A. ABU-SHEISHAA1; AHMED M. S. BAYOUMY1; KARIMA A. BAHGAT2 | ||||
1Department of Medical Parasitology, Faculty of Medicine | ||||
2Department of Medical Parasitology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||||
Abstract | ||||
Toxocariasis is one of the commonest zoonosis parasites worldwide, particularly in sheep-raising countries. Epilepsy is an important health problem in developing countries. The study assessed the seropositivity of toxocariasis in Egyptian idiopathic epileptic children. A case-control study was conducted on 125 children (1-18 years) with idiopathic epilepsy (patients) and 72 non-epileptic normal children (controls). All children underwent history taking, clinical examination, lab investigations, ELISA, and WB seropositivity to detect toxocariasis. The results showed no significant difference in age, sex, and socioeconomic level, but a significant difference was in residence and pet dogs between patients and controls (p < 0.05). Also, the Toxocara infection (ELISA) among patients was 41.6% versus 23.6% among controls and (Immunoblotting) 17.6% versus 5.5% respectively. There was an association between toxocariasis and epilepsy, with significant difference between patients and controls (P<0.05). Seropositivity was more in epileptic with generalized than partial seizures (p=0.06). As risk factors, residence and eating raw/undercooked meat showed significant difference and pet dogs and soil contact showed a highly significant difference in toxocariasis seropositive patients (P<0.05). | ||||
Keywords | ||||
Egyptian children; Toxocariasis; Idiopathic epilepsy | ||||
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