Spectrophotometric Determination of Catechol and Resorcinol By Oxidative Coupling With 2,4-Dinitrophenyl Hydrazine | ||||
| Egyptian Journal of Chemistry | ||||
| Article 36, Volume 64, Issue 9, September 2021, Page 5061-5065 PDF (362.4 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2021.57506.3253 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Dawood Habboo Mohammed; Farha Khalaf Omar | ||||
| Department of Chemistry, Education College for Girls, University of Mosul-Iraq. | ||||
| Abstract | ||||
| A simple, fast and sensible spectrophotometric method was developed for the determination of carvedilol. The method is based on the oxidative coupling reaction of the compound with phenothiazine in the presence of potassium dichromate as oxidant to form a stable pink-red color product showing maximum absorption at 551nm. Molar absorptivities are 1.625 ×104 l. Mol-1, cm-1. The Beer law has been complied with in a range from (1 to 12) ppm. This method has been successfully applied to carvedilol analysis in various pharmaceutical formulations. | ||||
| Keywords | ||||
| Spectrophotometry; carvedilol; Oxidative coupling | ||||
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