Prevalence of Epstein - Barr virus infection in Hepatitis C | ||||
| Egyptian Academic Journal of Biological Sciences, G. Microbiology | ||||
| Article 3, Volume 6, Issue 1, June 2014, Page 29-36 PDF (468.39 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/eajbsg.2014.16627 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Hussam Ghanem1; Sahar Shoman1; Mohamed Nabil1; Ashraf Tabl2 | ||||
| 1Department of Microbiology, Faculty of Science, Ain Shams University, Cairo, Egypt | ||||
| 2Department of Biomedical Technology, National Research Center, Giza, Egypt | ||||
| Abstract | ||||
| Background: Epstein - Barr virus (EBV) may be an omnipresent, common infective agent of severe illness in patients with impaired immune functions. Reactivation of Epstein-Barr virus in immunocompetent host is typically symptomless, however could deteriorate the prognosis of patient with chronic illness. Objectives: This study was conducted to detect EBV infection in patients with chronic hepatitis C virus (HCV) infections and to point out the effects of EBV-HCV co-infections on liver enzymes activity. Study design: Expression of EBV-DNA was determined in Serum samples by nested polymerase chain reaction (nested-PCR) method. There were 79 chronic HCV within the study group. Control group consisted of 52 cases without viral hepatitis. Results: EBV-DNA infection was demonstrated in 29% of chronic HCV patients. Although alanine aminotransferase (ALT) and (AST) levels of EBV-infected HCV patients were increased. Conclusion: We conclude that EBV infection is common in chronic HCV patients, who can be regarded as patients at high risk for EBV disease. | ||||
| Keywords | ||||
| Epstein; Barr virus (EBV) Hepatitis C virus | ||||
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