Prevalence and antibiotic susceptibility of methicillin-resistant Staphylococcus aureus isolated in Makkah hospitals | ||||
| Egyptian Academic Journal of Biological Sciences, G. Microbiology | ||||
| Article 6, Volume 6, Issue 1, June 2014, Page 59-65 PDF (237.34 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/eajbsg.2014.16630 | ||||
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| Authors | ||||
| Atif H. Asghar; Omar B. Ahmed | ||||
| Department of Environmental and Health Research, The Custodian of the Two Holy Mosques Institute for Hajj and Omraa, Umm Al-Qura University, Makkah, Saudi Arabia | ||||
| Abstract | ||||
| This study aimed toreport the frequency of MRSA among S. aureus isolates from patients in Makkah hospitals in Saudi Arabia and described the antimicrobial resistance profile of the MRSA isolates. 206 non-duplicated S. aureus clinical isolates were identified in the five main tertiary care hospitals in Makkahwithstandard microbiological methods. MRSA wer identified by Oxoid penicillin binding protein (PBP2′) latex agglutination test, and confirmed by the oxacillin-salt agar-screening test. The antimicrobial susceptibility of all MRSA isolates were assessed using a VITEK 2 Compact 15 identification system.MRSA was 55.3% and most frequently isolated from the intensive care unit 37%. Of the patients infected with MRSA, the majority were men 60%, and 25% were over 60 years old. Of the MRSA strains isolated, 41% were from skin and wound swabs. The resistance rates among MRSA isolates for penicillin G, oxacillin, and vancomycin were 100%, 100%, and 0.9%, respectively. Our results indicated that the prevalence of MRSA in Makkah hospitals was generally high. vancomycin, teicoplanin, and the oxazolidinone linezolid were considered the drugs of choice for the treatment of MRSA infections. | ||||
| Keywords | ||||
| MRSA; S. aureus; Oxacillin; resistance; Antimicrobial; Mannitol agar | ||||
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