Phenolic constituents from the leaves of Tylophora indica and their antioxidant activities | ||||
Zagazig Journal of Pharmaceutical Sciences | ||||
Article 3, Volume 20, Issue 1, June 2011, Page 22-29 PDF (2.47 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/zjps.2011.167340 | ||||
View on SCiNiTO | ||||
Authors | ||||
Mohammed Hussein ; Ehab Mostafa; El-Sayed El-Ghaly; Ehab Ragab | ||||
Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt | ||||
Abstract | ||||
Four flavonoids; kaempferol-3-O-galactoside (trifolin) [1], quercetin-3-O-galactoside (hyperoside) [2], quercetin-3-O- glucoside (isoquercitrin) [3] and kaempferol-3-O-rutinoside [4] together with chlorogenic acid [5] and chlorogenic acid methyl ester [6] have been isolated and purified for the first time from the leaves of Tylophora indica by HPLC. The structures were elucidated by the application of MS, IR, UV, ID- and 2D-NMR spectroscopic analyses and by comparison with literature data. All compounds 1-6 were found to exhibit antioxidant effects, based on the scavenging activity of the stable 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical. | ||||
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