POST-EXTUBATION SORE THROAT; HOW FAR NEBULIZ

Mohamed, Gihan Seif El Nasr; Farag, Hanan Mahmoud; Mostafa, Raham Hasan; Aly, Soaad Mostafa Mohammed

doi:10.21608/asmj.2021.167364

	POST-EXTUBATION SORE THROAT; HOW FAR NEBULIZ
Ain Shams Medical Journal
Article 10, Volume 72, Issue 1, March 2021, Page 119-127 PDF (719.96 K)
Document Type: Original Article
DOI: 10.21608/asmj.2021.167364
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Authors
Gihan Seif El Nasr Mohamed¹; Hanan Mahmoud Farag¹; Raham Hasan Mostafa¹; Soaad Mostafa Mohammed Aly²^{, 3}
¹Anesthesia, Intensive Care and Pain Management Department, Faculty of Medicine, Ain Shams University, Egypt.
²Anesthesia, Intensive Care and Pain Management Department, Faculty of Medicine, Ain Shams University, Egypt.+
³Tahrir General Hospital, Ministry of Health, Cairo, Egypt.
Abstract
Background: Post-operative sore throat (POST) is a frequent complaint that occurs in 21–65% of patients receiving general anes-thesia (GA) with endotracheal intubation. Effective prevention of postoperative sore throat is thus needed. The inhaled corticosteroids deliver the drug to the site of action without systemic effects. Dexame-thasone is a potent synthetic glucocorticoid with anti-inflammatory ef-fects. Aim of work: To assess how far nebulized dexamethasone de-creases the incidence of POST and hoarseness of voice. Patients and Methods: This double blinded double armed placebo controlled randomized clinical trial was conducted on 60 people divided into 2 groups; Group D: 30 patients received dexamethasone 8 mg in 5 ml normal saline nebulized 15 minutes before general anesthesia and en-dotracheal intubation. Group S: 30 patients received 5 ml normal saline nebulization 15 minutes before general anesthesia and endotracheal in-tubation. Results: Patients’ characteristics (age, sex, weight, ASA and Mal-lampati classification), duration of surgery, type of surgery, intuba-tion attempts and site of endotracheal tube shows non-significant dif-ference between both groups. Peri-nebulization hemodynamics, shows non-significant difference between both groups as regards heart rate and mean arterial blood pressure at all examined timings. Conclusions: In our study the incidence of POST was 2 (6.7) which mean that the pre-operative single dose of nebulized dexame-thasone 8 mg effectively can attenuates the incidence and severity of POST following GA with endotracheal intubation.
Keywords
Post-operative sore throat; General anesthesia; Neb-ulized dexamethasone decreases


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