LEVOSEMINDAN VERSUS INTRA-AORTIC BALLOON PUMP IN LOW EJECTION FRACTION CABG PATIENTS
Azzab, S., Elnahas, Y., Elkelany, I., Moharm, A. (2021). LEVOSEMINDAN VERSUS INTRA-AORTIC BALLOON PUMP IN LOW EJECTION FRACTION CABG PATIENTS. EKB Journal Management System, 72(1), 139-150. doi: 10.21608/asmj.2021.167369
Shereif Elsayed Soliman Azzab; Yasser Mahmoud Elnahas; Ibrahim Shawky Elkelany; Ahmed Mohamed Abd El-Salam Moharm. "LEVOSEMINDAN VERSUS INTRA-AORTIC BALLOON PUMP IN LOW EJECTION FRACTION CABG PATIENTS". EKB Journal Management System, 72, 1, 2021, 139-150. doi: 10.21608/asmj.2021.167369
Azzab, S., Elnahas, Y., Elkelany, I., Moharm, A. (2021). 'LEVOSEMINDAN VERSUS INTRA-AORTIC BALLOON PUMP IN LOW EJECTION FRACTION CABG PATIENTS', EKB Journal Management System, 72(1), pp. 139-150. doi: 10.21608/asmj.2021.167369
Azzab, S., Elnahas, Y., Elkelany, I., Moharm, A. LEVOSEMINDAN VERSUS INTRA-AORTIC BALLOON PUMP IN LOW EJECTION FRACTION CABG PATIENTS. EKB Journal Management System, 2021; 72(1): 139-150. doi: 10.21608/asmj.2021.167369

LEVOSEMINDAN VERSUS INTRA-AORTIC BALLOON PUMP IN LOW EJECTION FRACTION CABG PATIENTS

Ain Shams Medical Journal
Article 12, Volume 72, Issue 1, March 2021, Page 139-150  XML PDF (725.38 K)
Document Type: Original Article
DOI: 10.21608/asmj.2021.167369
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Authors
Shereif Elsayed Soliman Azzab1; Yasser Mahmoud Elnahas1; Ibrahim Shawky Elkelany1; Ahmed Mohamed Abd El-Salam Moharm2
1Cardiothoracic Surgery, Faculty of Medicine Ain Shams University, Egypt.
2Nasser Institute for research and treatment, Ministry of Health, Cairo, Egypt.
Abstract
Background: Preoperative left ventricular dysfunction is an independent risk factor for perioperative mortality and morbidity and is also associated with postoperative low cardiac output syndrome. IABP improved outcomes in high-risk cardiac patients. However, installation of the balloon has many disadvantages. Recently, a new drug named Levosimendan is commonly used as an inotropic support. it does not increase oxygen demand of myocardium.
Aim of the work: The purpose of our study was to compare the efficiency of levosimendan versus intra-aortic balloon pump in patients with poor left ventricular function undergoing coronary artery bypass grafting (CABG) with ejection fraction less than 35%.
Patients and Methods: sixty patients were randomized into 2 groups, according to the treatment they received - either levosimendan (Group A) or intra-aortic balloon counter pulsation (Group B). and compared with respect to The use of inotropic drugs, weaning from CPB, Hemodynamics, transfusion requirements, ICU stay, hospital stay and in-hospital mortality.
Results: There were no differences in preoperative characteristics including patients’ age, sex, BMI, and comorbidities. The Levosemindan group had reduced transfusion requirements and shorter ICU stay as compared to IABP group.
Conclusion: levosimendan infusion after induction of anesthesia is a good choice with an acceptable option in comparison to IABP. The use of levosimendan in high-risk cardiac patients is comparable to IABP in improving hemodynamics during and after conventional on-pump CABG and results in a shorter ICU stay.
Keywords
CABG; Levosmindan; Intra aortic balloon pump; Left ventricular dusfunction
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