SYNTHESIS OF SOME MALEIMIDE DERIVATIVES VIA REGIO AND STEREOSELECTIVE REDUCTION USING SODIUM BOROHYDRIDE
Abdel-Fattah, H., El-Bermawy, M., Kadry, A., Al-Ashmawi, M., Martin, H. (2007). SYNTHESIS OF SOME MALEIMIDE DERIVATIVES VIA REGIO AND STEREOSELECTIVE REDUCTION USING SODIUM BOROHYDRIDE. EKB Journal Management System, 16(2), 27-34. doi: 10.21608/zjps.2007.169384
Hanan Abdel-Fattah; Mohamed El-Bermawy; Azza Kadry; Mohamed Al-Ashmawi; H.D. Martin. "SYNTHESIS OF SOME MALEIMIDE DERIVATIVES VIA REGIO AND STEREOSELECTIVE REDUCTION USING SODIUM BOROHYDRIDE". EKB Journal Management System, 16, 2, 2007, 27-34. doi: 10.21608/zjps.2007.169384
Abdel-Fattah, H., El-Bermawy, M., Kadry, A., Al-Ashmawi, M., Martin, H. (2007). 'SYNTHESIS OF SOME MALEIMIDE DERIVATIVES VIA REGIO AND STEREOSELECTIVE REDUCTION USING SODIUM BOROHYDRIDE', EKB Journal Management System, 16(2), pp. 27-34. doi: 10.21608/zjps.2007.169384
Abdel-Fattah, H., El-Bermawy, M., Kadry, A., Al-Ashmawi, M., Martin, H. SYNTHESIS OF SOME MALEIMIDE DERIVATIVES VIA REGIO AND STEREOSELECTIVE REDUCTION USING SODIUM BOROHYDRIDE. EKB Journal Management System, 2007; 16(2): 27-34. doi: 10.21608/zjps.2007.169384

SYNTHESIS OF SOME MALEIMIDE DERIVATIVES VIA REGIO AND STEREOSELECTIVE REDUCTION USING SODIUM BOROHYDRIDE

Zagazig Journal of Pharmaceutical Sciences
Article 4, Volume 16, Issue 2, December 2007, Page 27-34  XML PDF (2.31 MB)
Document Type: Original Article
DOI: 10.21608/zjps.2007.169384
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Authors
Hanan Abdel-Fattah email 1; Mohamed El-Bermawy1; Azza Kadry1; Mohamed Al-Ashmawi1; H.D. Martin2
1Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt
2Institut fur Organic Chemie and Makromolekular Chemie, Heinrich-Hein-Universistät, Dusseldorf Universität,Germany
Abstract
Synthesis of specific maleimide derivatives was performed through the stereospecific use of sodium borohydride. The reduction took place on only one of the carbonyl which is adjacent to the phenylamino group or the alky1 amino group. Our results were confirmed by the presence of the formed hydroxyl group using chromatographic and spectroscopic techniques.
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