MATERNAL SERUM CALCIUM AND TRACE ELMENTS; COPPER AND ZINC AMONG PRE-ECLAMPTIC WOMEN IN CAIRO, EGYPT | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 6, Volume 41, Issue 1, October 2010, Page 520-531 PDF (227.37 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2010.16951 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Essam A. El-Moselhy1; Hesham H. Amin2; Hani M. Abd El-Aal3 | ||||
| 1Departments of Community Medicine | ||||
| 2Clinical Pathology Faculty of Medicine, Al-Azhar University | ||||
| 3Obstetric & Gynecology Faculty of Medicine, Al-Azhar University | ||||
| Abstract | ||||
| Introduction: Low levels of blood calcium (Ca) and trace elements are observed in patients with pre-eclampsia (PE). Among these patients low serum Ca, copper (Cu) and zinc (Zn) may be one of the disease causes. Objectives: The aim of this study was to find out the serum biochemical profile of these elements in the studied pre-eclamptic women. Subjects and methods: A case- control, hospital based study design was used. All the cases and controls were examined laboratory. Results: Maternal mean serum Ca, Cu and Zn were lower among pre-eclamptic cases compared to normal pregnant controls with statistically significant differences (P= 0.000 for each of them). Further, maternal mean serum Ca, Cu and Zn were lower among the severe PE cases compared to the mild cases with statistically significant differences (P=0.002, 0.000 and 0.000, respectively). Also, these low elements; Ca, Cu and Zn were significantly correlated factors with severe PE (P=0.01, 0.03 and 0.01, respectively). Recommendations: Early ante-natal care and treatment for pre-eclamptic women are recommended. Ca, Cu and Zn supplementation may be a cost effective method to prevent PE. Prospective population based studies are needed in different areas in Egypt and on large number of pregnant women to determine possible PE risk factors. | ||||
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