Detection of Visceral adiposity by Ultrasonography and its relation to insulin resistance in HCV patients | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 9, Volume 41, Issue 1, October 2010, Page 551-565 PDF (1.71 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejhm.2010.16954 | ||||
View on SCiNiTO | ||||
Authors | ||||
Mostafa K. Mohamed1; Gamal Esmat2; Mohamed Said2; Mohamed Abdel- Hamid3; Mohamed Hassany4; Mohamad A. Hassanein4; Kamal A. El- Atrebi4 | ||||
1Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University. | ||||
2Department of Tropical Medicine, Cairo University. | ||||
3Viral Hepatitis Research Laboratory, National Hepatology and Tropical Medicine Research Institute | ||||
4Department of Tropical Medicine, National Hepatology and Tropical Medicine Research Institute. | ||||
Abstract | ||||
Background:HepatitisCisamajorcauseofliver-relatedmorbidityandmortalityandrepresentsa majorpublichealthprobleminEgyptandworldwide.Ultrasonographyisasimplenon-invasive methodfordetectionofvisceralfat,whichisdirectly,correlatedwithinsulinresistance(IR)aswellas developmentoftype2diabetesmellitus. Aim:ToassessthevalidityofdetectionofvisceraladiposetissueareawithUltrasonographyandits correlationwithIRinHCVpatients Materials&Method:Thestudyparticipantsweresubcategorizedintotwogroups,Group(I): included867healthysubjectswithnegative(HCV)RNAasacontrolgroup.Group(II):included277 patientswithchronicHCVasastudygroup.The2groupsweresubjectedtothoroughhistorytaking, fullclinicalexamination,Anthropometricstudy,ultrasonographicexaminationandlaboratory investigationsincludingliverfunctions,viralmarkers,andqualitativePCRforHCVRNA,lipid profile&glucoseprofile. Results:Thisstudyrevealedthatultrasonographyisasimple,non-invasive,safemethodindetection ofvisceraladiposity,whichiscorrelatedsignificantlywithIRinchronicHCVpatients. | ||||
Keywords | ||||
HCV-Insulinresistance-Ultrasonography-Visceral adiposity | ||||
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