TOXICOLOGICAL EFFECTS OF THE ORAL ADMINISTRATION OF THE AQUEOUS EXTRACT FROM CALLIGONUM COMOSUM TO RATS
Harraz, F., Farah, M., Abdel-Aziz, S. (1993). TOXICOLOGICAL EFFECTS OF THE ORAL ADMINISTRATION OF THE AQUEOUS EXTRACT FROM CALLIGONUM COMOSUM TO RATS. EKB Journal Management System, 2(2), 1-9. doi: 10.21608/zjps.1993.169727
Fathalla Harraz; Mohamed Farah; Sayed Abdel-Aziz. "TOXICOLOGICAL EFFECTS OF THE ORAL ADMINISTRATION OF THE AQUEOUS EXTRACT FROM CALLIGONUM COMOSUM TO RATS". EKB Journal Management System, 2, 2, 1993, 1-9. doi: 10.21608/zjps.1993.169727
Harraz, F., Farah, M., Abdel-Aziz, S. (1993). 'TOXICOLOGICAL EFFECTS OF THE ORAL ADMINISTRATION OF THE AQUEOUS EXTRACT FROM CALLIGONUM COMOSUM TO RATS', EKB Journal Management System, 2(2), pp. 1-9. doi: 10.21608/zjps.1993.169727
Harraz, F., Farah, M., Abdel-Aziz, S. TOXICOLOGICAL EFFECTS OF THE ORAL ADMINISTRATION OF THE AQUEOUS EXTRACT FROM CALLIGONUM COMOSUM TO RATS. EKB Journal Management System, 1993; 2(2): 1-9. doi: 10.21608/zjps.1993.169727

TOXICOLOGICAL EFFECTS OF THE ORAL ADMINISTRATION OF THE AQUEOUS EXTRACT FROM CALLIGONUM COMOSUM TO RATS

Zagazig Journal of Pharmaceutical Sciences
Article 1, Volume 2, Issue 2, December 1993, Page 1-9  XML PDF (4.89 MB)
Document Type: Original Article
DOI: 10.21608/zjps.1993.169727
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Authors
Fathalla Harraz email 1; Mohamed Farah2; Sayed Abdel-Aziz2
1Dept of Vet. Med., College of Agric. and Vet. Med., King Saud Univ., Qassim, Bureidah, Saudi Arabia
2Dept of Vet. Med., College of Agric. and Vet. Med., King Saud Univ., Qassim, Bureidah, Saudi Arabia
Abstract
Adult male Wistar rats were given daily oral doses of the lyophilized aqueous extract of Calligonum comosum at the rate of 400 mg/kg (b.wt.) for 4 weeks. The biochemical changes included a significant increase in the levels of serum Calcium and SUN (P < 0.05). On the other hand, decreased values were noted in the levels of serum albumin (P < 0.01). Haematological changes showed increased lymphocyte count (P < 0.05), whereas, decreases were noted in the levels of Hb (P < 0.01) and total WBCS count (P < 0.05), in addition to panleucocylopenia (P < 0.05) involving all the granulocytes and the monocytes ( P < 0.001).
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