Intra-umbilical Oxytocin versus Methyl Ergometrine in the Third Stage of Labor: A Comparative Study from an Egyptian Tertiary Care Hospital | ||||
| The Egyptian Journal of Fertility of Sterility | ||||
| Article 6, Volume 25, Issue 2 - Serial Number 11106352, May 2021, Page 47-52 PDF (1.41 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/egyfs.2021.170465 | ||||
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| Author | ||||
| Ahmed A. El-Zayadi | ||||
| Department of Obstetrics and Gynecology, Mansoura University Hospitals, Elgomhouria St., City 35111, Dakahlia, Egypt | ||||
| Abstract | ||||
| Abstract Recently, the active management of the third stage of labor has become a routine practice. In this study we compared two different ecobolics which were oxytocin and methyl ergometrine through intra-umbilical route. The method: the trial divided the included pregnant full term (>37 weeks) women in two groups randomly; one for 0.2 mg methyl ergometrine and the second 10 units oxytocin. The outcomes were on the short term; estimated blood loss (EBL), the need to add another ecobolic, vomiting, blood pressure changes and the duration of the third stage, and the long-term outcomes were hemoglobin levels and the need for surgical or medical uterine evacuation. The results: the mean blood loss was 155± 50.45ml and 167± 45.76 in the methyl ergometrine and the oxytocin groups respectively. Three cases in the oxytocin group (3%) required additional methyl ergometrine while in the ergometrine group only one case was given an additional oxytocin (1%). No vomiting was reported in both groups and there were trivial changes in blood pressure. In the oxytocin group, the third stage duration was average 3.03± 1.02 min in comparison to 2.98± 1.54min in the ergometrine group. Neither did those cases who were injected methyl ergometrine have significant changes in the hemoglobin levels nor did they need uterine evacuation. However, only one case in the oxytocin side required blood transfusion due to uterine atony. Conclusion: intra-umbilical methyl ergometrine should be considered as an effective safe ecobolic in the third stage of labor. | ||||
| Keywords | ||||
| Keywords: Third stage; ecobolics; postpartum hemorrhage; intra-umbilical; oxytocin; ergometrine | ||||
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