Pharmacological screening of some Egyptian marine algae and encapsulation of their bioactive extracts in calcium alginate beads
El Nemr et al., A. (2021). Pharmacological screening of some Egyptian marine algae and encapsulation of their bioactive extracts in calcium alginate beads. EKB Journal Management System, 25(2), 1025-1052. doi: 10.21608/ejabf.2021.170631
Ahmed El Nemr et al.. "Pharmacological screening of some Egyptian marine algae and encapsulation of their bioactive extracts in calcium alginate beads". EKB Journal Management System, 25, 2, 2021, 1025-1052. doi: 10.21608/ejabf.2021.170631
El Nemr et al., A. (2021). 'Pharmacological screening of some Egyptian marine algae and encapsulation of their bioactive extracts in calcium alginate beads', EKB Journal Management System, 25(2), pp. 1025-1052. doi: 10.21608/ejabf.2021.170631
El Nemr et al., A. Pharmacological screening of some Egyptian marine algae and encapsulation of their bioactive extracts in calcium alginate beads. EKB Journal Management System, 2021; 25(2): 1025-1052. doi: 10.21608/ejabf.2021.170631

Pharmacological screening of some Egyptian marine algae and encapsulation of their bioactive extracts in calcium alginate beads

Egyptian Journal of Aquatic Biology and Fisheries
Article 58, Volume 25, Issue 2, March and April 2021, Page 1025-1052  XML PDF (1.08 MB)
Document Type: Original Article
DOI: 10.21608/ejabf.2021.170631
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Author
Ahmed El Nemr et al.
Abstract
The pharmacological screening of some crude extracts obtained from different marine algae collected from the Mediterranean in Alexandria region in Egypt has been conducted. The methanol, butanol, and ethyl acetate extracts of Pterocladia capillacea, Ulva lactuca and Corallina mediterranea showed inhibitory activity against the growth of Lemna minor plant. The methanol and petroleum ether extracts of Ulva lactuca (VII) exhibited significant antioxidant activity 92.2 and 84.6%, respectively, in the DPPH free radical scavenging assay. The methanol and ethyl acetate extracts of Pterocladia capillacea and Corallina mediterranea showed remarkable inhibitory activity against butyrylcholinesterase. The ether extract of Pterocladia capillacea (III) and the petroleum ether extract of Ulva lactuca (VII) exhibited high antiglycation activity (69.4% and 65% with IC50 of 0.0596 ± 0.0447 mM and 0.138 ± 0.0441 mM, respectively). The ether extract of Ulva fasciata (I) potently inhibited the oxidative burst activity of phagocytes from whole blood analysis (97.99%) at a concentration of 400 µg/mL.  Scanning by electron microscope (SEM) showed successful encapsulation of the bioactive algal extracts into calcium alginate beads. Tested marine macroalgae have the potential to produce bioactive metabolites with significant antifungal, phytotoxic, antioxidant, anticholinesterase, antiglycation, and immunomodulating activities.
Keywords
Ulva lactuca; Ulva fasciata; Pterocladia capillacea; Corallina Mediterranea; Biological activity; Encapsulation
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