IN-VITRO ANTIBACTERIAL ACTIVITY AND CHEMICAL COMPOSITION OF SYRIAN ERICA MANIPULIFLORA ESSENTIAL OIL | ||||
| Bulletin of Pharmaceutical Sciences Assiut University | ||||
| Article 6, Volume 44, Issue 1, June 2021, Page 63-71 PDF (469.35 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bfsa.2021.174131 | ||||
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| Authors | ||||
| Lamis Talal Tlas1; Isam Chamaa1; Jalal Fandi1; Emad Al Haddad2 | ||||
| 1Department of Pharmacognosy, Faculty of Pharmacy, Damascus University, Damascus, Syria | ||||
| 2Department of Pharmaceutical Chemistry and Drug Control, Faculty of Pharmacy, Al Baath University, Homs, Syria | ||||
| Abstract | ||||
| In current research, we aimed to investigate the chemical composition of the EO of Erica manipuliflora extracted in two growth periods (before flowering and full flowering periods), to evaluate the differences between the two EOs in antibacterial activity against four pathogenic bacteria (Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Salmonella enteritidis). Results showed the existence of 17 and 23 volatile components in the EOs extracted from E. manipuliflora before flowering and in full flowering periods, respectively. The main components in EO extracted from the plant before flowering period were Germacrene-D, tau-cadinol, β-caryophellene, Trans-pinocarveol and β-pinene; which represented 35.02, 26.36, 14.78, 9.25 and 3.65%, respectively. The EO extracted from the plant collected in full flowering period were β-citral, β-pinene, Germacrene-D, tau-cadinol and Trans-pinocarveol, which represented 22.26, 18.50, 16.90, 11.89 and 5.58%, respectively. The EO extracted from E. manipuliflora in the full flowering period was more active than that extracted before flowering period towards the bacterial species mentioned above. The most sensitive bacterium towards E. manipuliflora EOs was Bacillus subtilis, while the most resistant one was Salmonella enteritidis. | ||||
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