HISTOPATHOLOGICAL, HISTOCHEMICAL AND PHYSIOLOGICAL STUDIES ON THE EFFECT OF THE INSECTICIDE "HOSTATHION" ON THE LIVER OF THE CATFISH CLARIAS gariepinus | ||||
Egyptian Journal of Aquatic Biology and Fisheries | ||||
Article 6, Volume 6, Issue 2, April 2002, Page 103-123 PDF (3.33 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejabf.2002.1742 | ||||
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Authors | ||||
Saber Sakr1; Soad Hanafy2; Nabila El-Dosouky3 | ||||
1-Zoology Department, Faculty of Science, Menufiya University, egypt | ||||
2Zoology Department, Faculty of Science, South Valley University, egypt | ||||
3Zoology Department, Faculty of Science, Tanta University, egypt | ||||
Abstract | ||||
In the present work experiments were carried out to investigate the hazardous effects of the organophosphorous insecticide (Hostathion) on the histology, histochemistry and physiology of the liver of the catfish (Clarias gariepinus) after exposure to LC50, VzLCso and ViLCso of the insecticide for different periods. The results showed that the histopathological changes induced in the liver were mainly represented by liver cord disarray, cytoplasmic vacuolization of the hepatocytes, damage of blood sinusoids, blood vessel congestion and inflammatory leucocytic infiltration. The histochemical observation revealed marked reduction in glycogen contents and total protein contents of the liver cells as compared with the control materiaL Physiologically, different treatments at different time intervals resulted in variable degrees of inhibition in 5'-nucleotidase and alkaline phosphatase activities. These changes were both concentration- and time- dependent. | ||||
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