Effect of vitamin D supplementation on patients with acne vulgaris: An intervention study | ||||
| The Egyptian Family Medicine Journal | ||||
| Article 16, Volume 5, Issue 1, May 2021, Page 177-187 PDF (420.37 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/efmj.2021.61198.1066 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Walaa M. Abdelaziz  1; Taghreed M. Farahat 2; Hala M. Shaheen3; Mohamed A. Gaber4; Nora A. khalil 5
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| 1Department of Family medicine, Faculty of Medidcine, Menofia University , Shebein El kom, Egypt | ||||
| 2Department of Family medicine-Faculty of Medicine- Menoufiya University | ||||
| 3Department of Family Medicine, Faculty of Medicine, menoufya University, Egypt. | ||||
| 4Dermatology department, faculty of medicine, menofia university | ||||
| 5family medicine department, Faculty of Medicine, Menoufia University. | ||||
| Abstract | ||||
| Background: Acne is a common chronic inflammatory disease of the skin. Vitamin-D is fat soluble vitamin with immunomodulatory function, its deficiency has been noticed in various skin diseases. Objectives: assess frequency of serum vitamin-D deficiency among acne vulgaris patients and the effect of vitamin-D supplementation on acne grading. Method: the study was conducted on two phases, phase I was a cross-sectional study included measuring serum vitamin D level for 80 acne patients attending dermatology clinic at Menoufia University Hospital. Phase II was case control study where studied acne patients with vitamin-D deficiency (66 patients) were randomly divided into two groups; one group (33 patients) were treated with free Oral vitamin-D 2000IU/ tablet for 2 months in addition to regular acne treatment. The other group (33 patients) received traditional treatment for acne without vitamin-D supplementation and both groups were followed up clinically for two months. Results: frequency of vitamin-D deficiency among studied patients was 82.5%, there was statistically significant relationship between vitamin-D deficiency and severity of acne. Vitamin-D deficiency is significantly prevalent among female patients (98.4%). There was significant improvement in acne grading after vitamin-D supplementation Conclusion and recommendation: There’s significant relation between vitamin-D deficiency and severity of acne vulgaris and vitamin -D has a good role in management of acne. So. It is recommended to evaluate the serum level of vitamin D in acne patients and provide vitamin D supplementation to vitamin D deficient patients beside topical treatments for acne. | ||||
| Keywords | ||||
| acne; vitamin-D; deficiency; vitamin-D supplements | ||||
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