ROLE OF ADVANCED MAGNETIC RESONANCE IMAGING TECHNIQUES IN DISTINCTION BETWEEN CEREBRAL ABSCESSES AND HIGH-GRADE NEOPLASMS. | ||||
| ALEXMED ePosters | ||||
| Article 128, Volume 3, Issue 2, June 2021, Page 59-60 | ||||
| Document Type: Preliminary preprint short reports of original research | ||||
| DOI: 10.21608/alexpo.2021.78612.1172 | ||||
 View on SCiNiTO | ||||
| Author | ||||
Yousra mohamed Ebrahim 
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| Department of Radiodiagnosis and Intervention, Faculty of Medicine, University of Alexandria. | ||||
| Abstract | ||||
| • Distinguishing between cerebral abscess and rim-enhancing tumor is a problem that is encountered frequently by radiologists. Conventional contrast-enhanced MRI reveals ring enhancement of a brain abscess that is similar to the ring enhancement of a necrotic high-grade glioma or metastasis. • Advanced MRI techniques (DWI, MRS and DSC MR perfusion) may be used to differentiate between cerebral abscesses and high grade brain neoplasms. • DWI is an advanced MRI technique that provides the physiological nature of the disease based on motion of water molecules across cell membrane. • DWI allows assessment of the cellularity of the lesion non-invasively, as cellular and subcellular elements significantly impede the mobility of water molecules, thus densely cellular lesions show restricted diffusion and hence low ADC values. • Magnetic Resonance spectroscopy (MRS) is a non-invasive diagnostic test for measuring biochemical changes in the brain, it MRS is capable of differentiating normal from pathologic brain. • Dynamic susceptibility contrast (DSC) perfusion MRI is a technique that allows derivation of relative cerebral blood volume (rCBV) maps on the basis of the susceptibility effect related to passage of MRI contrast material through tissue. • It provides noninvasive physiologic measurements of tumor vascularity and relative cerebral blood volume (rCBV) maps, which can be used to identify and quantify areas of neovascularization. • We try to evaluate the role of advanced MRI techniques (DWI, MRS, DSC PERFUSION) to reach a final diagnosis in a case of brain abscess versus a cystic or necrotic tumor. | ||||
| Keywords | ||||
| ADVANCED; ABSCESSES; HIGH-GRADE | ||||
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