Cytogenetic and biochemical studies on the effect of DDB in albino mice and their embryos. | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 12, Volume 28, Issue 1, July 2007, Page 439-447 PDF (267 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejhm.2007.17673 | ||||
View on SCiNiTO | ||||
Authors | ||||
Adel El Rokeeb1; Amira Abd El Raouf2 | ||||
1AL. Azhar University Faculty of Medicine (Boys branch) Egypty | ||||
2National Research Centre Cell Biology Department Dokki - Egypt | ||||
Abstract | ||||
Introduction: DDB (Dimethyl – 4,4/ – dimethoxy – 5,6,5/,6/ – dimethlene – dioxybi- phenyl – 2,2 – dicarboxylate) is important drug of medicine not expensive since large number of people are using it in virus B and C cases for very large periods extend to many years. The protective of DDB on chemically induced damage was studied in primary cultures of mammals hepatocytes. Results:This work study of cytogenetic and biochemical effect of DDB, in mice using the chromosomes of bone marrow of male and pregnant female shown some changes with liver embryos. Also germ cells of testes given non significant aberration when compared with control. As well as some biochemical parameters in serum and tissues, shown non significant changes in nucleic acid, total protein, total cholesterol, total glucose, total triglycerides and lactate dehydrogenase (LDH). Also, enzyme | ||||
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