Impact of dietary Spirulina (arthrospira) platensis on growth performance, gene expression and antioxidant status of quail challenged with salmonella enteritidis.
Abd EL-Dayem, G., Saleh, G., Abd EL- Elwahab, R. (2021). Impact of dietary Spirulina (arthrospira) platensis on growth performance, gene expression and antioxidant status of quail challenged with salmonella enteritidis.. EKB Journal Management System, 22(2), 38-47. doi: 10.21608/mvmj.2021.66416.1040
Ghada Abd EL-Dayem; Gehan Saleh; Reham Abd EL- Raouf Abd EL- Elwahab. "Impact of dietary Spirulina (arthrospira) platensis on growth performance, gene expression and antioxidant status of quail challenged with salmonella enteritidis.". EKB Journal Management System, 22, 2, 2021, 38-47. doi: 10.21608/mvmj.2021.66416.1040
Abd EL-Dayem, G., Saleh, G., Abd EL- Elwahab, R. (2021). 'Impact of dietary Spirulina (arthrospira) platensis on growth performance, gene expression and antioxidant status of quail challenged with salmonella enteritidis.', EKB Journal Management System, 22(2), pp. 38-47. doi: 10.21608/mvmj.2021.66416.1040
Abd EL-Dayem, G., Saleh, G., Abd EL- Elwahab, R. Impact of dietary Spirulina (arthrospira) platensis on growth performance, gene expression and antioxidant status of quail challenged with salmonella enteritidis.. EKB Journal Management System, 2021; 22(2): 38-47. doi: 10.21608/mvmj.2021.66416.1040

Impact of dietary Spirulina (arthrospira) platensis on growth performance, gene expression and antioxidant status of quail challenged with salmonella enteritidis.

Mansoura Veterinary Medical Journal
Article 1, Volume 22, Issue 2, June 2021, Page 38-47  XML PDF (1.77 MB)
Document Type: Original Articles
DOI: 10.21608/mvmj.2021.66416.1040
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Authors
Ghada Abd EL-Dayem email orcid 1; Gehan Saleh1; Reham Abd EL- Raouf Abd EL- Elwahab2
1poultry Diseases Department, animal health research institute, (Mansoura branch),Agriculture Research Center, P.O.Box 246 Dokki,12618-Giza, EGYPT
2Biochemistry, Nutritional Deficiency DEPARTMENT, Animal Health Research Institute(AHRI) (Mansoura branch) Agriculture Research Center (ARC), P.O. Box 246 Dokki, 12618 – Giza, Egypt.
Abstract
Abstract
Objective: To investigate the effect of dietary Spirulina platensis supplementation on growth performance, organ colonization, expression of inflammatory-related genes, and antioxidant status in quail challenged with Salmonella enteritidis.
Design: Randomized controlled experimental study.
Animals: hundred eighty-seven-day-old Japanese quail.
Procedures: birds were randomly allocated into 6 equal groups. G1, G2, and G3: non challenged and fed abasal diet supplemented with Spirulina at 0, 1, and 2 g/kg diet, respectively. G4, G5, and G6: challenged and fed a basal diet supplemented with Spirulina at 0, 1, and 2 g/kg diet, respectively. At 21 days of age, all challenged groups were orally inoculated with 1ml of (1.00x107 Salmonella enteritidis/ml). The collected samples were serum for determining biochemical and antioxidant parameters, cecal tissue samples for determination of gene expression of inflammatory-related genes, and tissue samples from liver, heart, spleen, and caecum for bacterial reisolation.
Results: The dietary supplementation of Spirulina significantly improved growth performance parameters and reduced organ colonization. The cecal pro-inflammatory gene expressions (IL-6, IL1 ß and TNFα) were significantly downregulated while the anti-inflammatory cytokine (IL-10) was significantly increased. In addition, gene expression of cecal serum amyloid (SAA) was significantly down-regulated. The antioxidant and serum biochemical parameters were improved.
Conclusion and clinical relevance: dietary supplementation of Spirulina could be a helpful strategy for mitigating the harmful effects of Salmonella enteritidis in quail.
Keywords
Salmonella enteritidis; quails; Spirulina platensis; Growth performance; Cytokines
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