Screening of High-Risk Patient by Uterine Artery Doppler Analysis in The 1st Trimester to Predict Early Onset Pre-Eclampsia
Mohamed, H., Badawy, A., Ismail, A. (2021). Screening of High-Risk Patient by Uterine Artery Doppler Analysis in The 1st Trimester to Predict Early Onset Pre-Eclampsia. EKB Journal Management System, 84(1), 1852-1857. doi: 10.21608/ejhm.2021.177620
Hasnaa Mohamed Elfouly Mohamed; Ahmed Mahmoud Moustafa Badawy; Ashraf Ghanem, Khaled Samir Ismail. "Screening of High-Risk Patient by Uterine Artery Doppler Analysis in The 1st Trimester to Predict Early Onset Pre-Eclampsia". EKB Journal Management System, 84, 1, 2021, 1852-1857. doi: 10.21608/ejhm.2021.177620
Mohamed, H., Badawy, A., Ismail, A. (2021). 'Screening of High-Risk Patient by Uterine Artery Doppler Analysis in The 1st Trimester to Predict Early Onset Pre-Eclampsia', EKB Journal Management System, 84(1), pp. 1852-1857. doi: 10.21608/ejhm.2021.177620
Mohamed, H., Badawy, A., Ismail, A. Screening of High-Risk Patient by Uterine Artery Doppler Analysis in The 1st Trimester to Predict Early Onset Pre-Eclampsia. EKB Journal Management System, 2021; 84(1): 1852-1857. doi: 10.21608/ejhm.2021.177620

Screening of High-Risk Patient by Uterine Artery Doppler Analysis in The 1st Trimester to Predict Early Onset Pre-Eclampsia

The Egyptian Journal of Hospital Medicine
Article 35, Volume 84, Issue 1, July 2021, Page 1852-1857  XML PDF (632.44 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2021.177620
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Authors
Hasnaa Mohamed Elfouly Mohamed email ; Ahmed Mahmoud Moustafa Badawy; Ashraf Ghanem, Khaled Samir Ismail
Department of Obstetrics and Gynecology, Faculty of Medicine - Mansoura University, Egypt
Abstract
Background: Preeclampsia (PE) is still a major obstetrical problem world-wide. First trimester prediction of PE is of great clinical importance, as it would allow clinicians to focus on high-risk groups and initiate prophylactic medical treatment. The first stage of pre-eclampsia begins in the first trimester by impaired placentation. High-resistant spiral arteries can be detected from the 11th week of gestation by uterine artery (UtA) Doppler examination.
Objective: To assess the relationship between 1st trimester uterine artery pulsatility index (UtA PI) and the development of early onset PE.Patients and Methods: Prospective observational study was performed at Mansoura University Hospital. This study was conducted on 109 pregnant women who attended their routine antenatal care visits at the Outpatient Obstetrics and Gynecology Clinic of Mansoura University Hospital.
Results: There were statistically high significant difference between both groups in the BMI (p = 0.003), and no statistically significant difference as regards the age, gravidity and gestational age (p > 0.05). Statistically significant difference was evident between two groups in the mean values of UtA PI (p = 0.028). The best cutoff value of UtA PI for the prediction of early onset preeclampsia was ≥ 2.03 with accuracy of 0.79, and that of BMI was ≥ 35 with accuracy of 0.93.
Conclusion: This study revealed that first trimester uterine artery Doppler can be used as a reliable screening test for prediction of preeclampsia in high risk women. It is a reliable, noninvasive method of examining uteroplacental perfusion. Abnormal UA Doppler ultrasonography (elevated PI) in 11–14 weeks' gestation can predict pre-eclampsia.
 
Keywords
Early onset pre-eclampsia; High risk patient; Screening; Uterine Artery Doppler
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