PHENOLIC CONSTITUENTS AND BIOLOGICAL ACTIVITY OF THE AERIAL PARTS OF THE EGYPTIAN LICORICE (GLYCYRRHIZA GLABRA L)
El-Domiaty, M., Abdel-Aziz, E., El-Shafae, A., Mohammed, M. (2003). PHENOLIC CONSTITUENTS AND BIOLOGICAL ACTIVITY OF THE AERIAL PARTS OF THE EGYPTIAN LICORICE (GLYCYRRHIZA GLABRA L). EKB Journal Management System, 12(1), 14-23. doi: 10.21608/zjps.2003.178045
Maher El-Domiaty; Ehsan Abdel-Aziz; Azza El-Shafae; Maged Mohammed. "PHENOLIC CONSTITUENTS AND BIOLOGICAL ACTIVITY OF THE AERIAL PARTS OF THE EGYPTIAN LICORICE (GLYCYRRHIZA GLABRA L)". EKB Journal Management System, 12, 1, 2003, 14-23. doi: 10.21608/zjps.2003.178045
El-Domiaty, M., Abdel-Aziz, E., El-Shafae, A., Mohammed, M. (2003). 'PHENOLIC CONSTITUENTS AND BIOLOGICAL ACTIVITY OF THE AERIAL PARTS OF THE EGYPTIAN LICORICE (GLYCYRRHIZA GLABRA L)', EKB Journal Management System, 12(1), pp. 14-23. doi: 10.21608/zjps.2003.178045
El-Domiaty, M., Abdel-Aziz, E., El-Shafae, A., Mohammed, M. PHENOLIC CONSTITUENTS AND BIOLOGICAL ACTIVITY OF THE AERIAL PARTS OF THE EGYPTIAN LICORICE (GLYCYRRHIZA GLABRA L). EKB Journal Management System, 2003; 12(1): 14-23. doi: 10.21608/zjps.2003.178045

PHENOLIC CONSTITUENTS AND BIOLOGICAL ACTIVITY OF THE AERIAL PARTS OF THE EGYPTIAN LICORICE (GLYCYRRHIZA GLABRA L)

Zagazig Journal of Pharmaceutical Sciences
Article 3, Volume 12, Issue 1, June 2003, Page 14-23  XML PDF (4.55 MB)
Document Type: Original Article
DOI: 10.21608/zjps.2003.178045
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Authors
Maher El-Domiaty email 1; Ehsan Abdel-Aziz2; Azza El-Shafae2; Maged Mohammed2
1Department of Pharmacognosy, Faculty of Pharmacy, University of Zagazig, Egypt.
2Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Abstract
Four isoflavones (glabrisoflavone, prunitin, santal and genisetin), two flavonols (kaempferol and quercetin) and one phenolic acid (4-hydroxy phenyl acetic acid) beside β-sitosterol and ß-sitosterol-O-glucoside, were isolated from the aerial parts of the Egyptian licorice (G. glabra). Santal, 4-hydroxy phenyl acetic acid and B-sitosterol-O-glucoside are reported here for the first time in the genus Glycyrrhiza. The structures of the isolated compounds were determined by IR, UV, MS, 1H-NMR and 13CNMR (2D experiments), as well as comparison with reference samples. Preliminary pharmacological testing of the total alcoholic extract and some of its fractions demonstrated potent anti-inflammatory and hepato-protective activities compared to hydrocortisone and silymarin, respectively.
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